Mlkl
MLKL(mixed lineage kinase domain-like)是与细胞凋亡相关的蛋白质。其激活状态涉及到其N-末端结构域的磷酸化,这种磷酸化导致MLKL的构象变化,从而促使其进入细胞膜,并引发细胞坏死。特别是在程序性坏死性细胞死亡(necroptosis)中发挥作用。在细胞受到特定信号刺激时,MLKL促进程序性坏死性细胞死亡,这种细胞死亡与免疫应答、炎症和组织修复等生物学过程有关。在疾病治疗领域中。,其磷酸化状态和活性受到广泛关, 对MLKL的研究对于了解坏死性细胞死亡的分子机制,尤其是在免疫相关疾病和炎症性疾病中发挥的作用,以及寻找相关的治疗策略非常重要。
热销产品
Recombinant Human Mixed lineage kinase domain-like protein (MLKL)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Mlkl Antibodies
Mlkl for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA850851LA01HU | MLKL Antibody | Human | ELISA, IHC |
CSB-PA850851LC01HU | MLKL Antibody, FITC conjugated | Human | |
CSB-PA003250 | MLKL Antibody | Human | WB, ELISA |
CSB-RA850851A358phHU | Phospho-MLKL (S358) Recombinant Monoclonal Antibody | Human | ELISA, IHC |
Mlkl Proteins
Mlkl Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP850851HU | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | Yeast |
CSB-EP850851HU | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |
CSB-BP850851HU CSB-MP850851HU CSB-EP850851HU-B |
Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP850851HUb2 | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |
CSB-EP850851HUb2 | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |
Mlkl Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP861529MO | Recombinant Mouse Mixed lineage kinase domain-like protein (Mlkl) | Yeast |
CSB-EP861529MO CSB-BP861529MO CSB-MP861529MO CSB-EP861529MO-B |
Recombinant Mouse Mixed lineage kinase domain-like protein (Mlkl) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mlkl Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-EP850851HUa0 | Recombinant Human Mixed lineage kinase domain-like protein (MLKL) | E.coli |