MSTN
MSTN,即肌生长抑制素,是一种在哺乳动物肌肉骨骼系统中起关键调控作用的分泌性蛋白,属于TGF-β超家族成员。其结构包括N-末端的分泌信号肽和半胱氨酸结构。MSTN通过与其受体结合,抑制肌肉细胞的生长、分化和增殖,从而调控肌肉的发育。在信号转导过程中,MSTN与胞质内受体形成复合物,进而激活Smads蛋白,使其磷酸化并进入细胞核调节靶基因表达。此外,MSTN还涉及MAPK和p38等信号通路的转导,对肌肉细胞增殖周期产生影响。MSTN的复杂结构和功能使其在生物学和医学领域具有广泛的应用前景,尤其在肌肉生长调控、疾病治疗及肉化剂开发等方面。
热销产品
Recombinant Horse Growth/differentiation factor 8 (MSTN)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MSTN Antibodies
MSTN for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA015057GA01HU | MSTN Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA11869A0Rb | MSTN Antibody | Human | ELISA, WB, IHC |
CSB-PA11869B0Rb | MSTN Antibody, HRP conjugated | Human | ELISA |
CSB-PA008776 | MSTN Antibody | Human,Mouse | IHC, ELISA |
CSB-PA293957 | MSTN Antibody | Human,Mouse,Rat | ELISA,IHC |
MSTN Proteins
MSTN Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP015057HU CSB-BP015057HU CSB-MP015057HU CSB-EP015057HU-B |
Recombinant Human Growth/differentiation factor 8 (MSTN) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP015057HU | Recombinant Human Growth/differentiation factor 8 (MSTN) | E.coli |
MSTN ELISA Kit
MSTN ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E11300h | Human Myostatin,MSTN ELISA Kit | serum, plasma, tissue homogenates | 0.312 ng/mL |