MRC1
甘露糖受体1（MCR1），又称为CD206,属跨膜蛋白，相对分子质量为166kDa，是M2型巨噬细胞标志物，具有高度特异性。MCR1主要分布于大多数巨噬细胞和未成熟的树突状细胞表面，作为模式识别受体来辨识病原体表面的糖蛋白和糖脂，因此其起到了识别抗原以及抗原提呈的作用。此外，MCR1在体循环中还起到了清除病理状态下产生的硫酸化糖蛋白激素和糖蛋白的作用。在巨噬细胞膜蛋白水解切割后,在外周发现可溶形式的MCR1。MCR1的可溶形式与膜形式相似，也识别硫酸化和甘露糖化的碳水化合物，并且可以改变先天性和适应性免疫应答。
研究表明肿瘤相关巨噬细胞参与肿瘤微环境，可促进多种肿瘤生成和转移，以M2型肿瘤相关巨噬细胞居多，在乳腺癌、卵巢癌、胰腺癌和前列腺按等肿瘤中都可发现其踪迹。MCR1作为M2型巨噬细胞标志物，具有高度特异性，可以作为恶性肿瘤诊断的潜在标志物。
MRC1 Antibodies
MRC1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA014782GA01HU | MRC1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA106212 | MRC1 Antibody | Human | ELISA,WB |
| CSB-PA006303 | MRC1 Antibody | Human | WB, ELISA |
| CSB-PA010220 | MRC1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA941963 | MRC1 Antibody | Human | ELISA,IHC |
| CSB-PA014783LA01HU | MRC1 Antibody | Human | ELISA |
| CSB-PA014783LD01HU | MRC1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA014783LC01HU | MRC1 Antibody, FITC conjugated | Human | |
| CSB-PA014783LB01HU | MRC1 Antibody, HRP conjugated | Human | ELISA |
MRC1 Proteins
MRC1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014783HU | Recombinant Human Macrophage mannose receptor 1 (MRC1), partial | Yeast |
| CSB-EP014783HU | Recombinant Human Macrophage mannose receptor 1 (MRC1), partial | E.coli |
| CSB-BP014783HU CSB-MP014783HU CSB-EP014783HU-B |
Recombinant Human Macrophage mannose receptor 1 (MRC1), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP014783HUa0 | Recombinant Human Macrophage mannose receptor 1 (MRC1), partial | E.coli |
MRC1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP338680SVG CSB-EP338680SVG CSB-BP338680SVG CSB-MP338680SVG CSB-EP338680SVG-B |
Recombinant Saccharomyces cerevisiae Mediator of replication checkpoint protein 1 (MRC1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MRC1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP723429MO CSB-EP723429MO CSB-BP723429MO CSB-MP723429MO CSB-EP723429MO-B |
Recombinant Mouse Macrophage mannose receptor 1 (Mrc1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MRC1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP889248SXV CSB-EP889248SXV CSB-BP889248SXV CSB-MP889248SXV CSB-EP889248SXV-B |
Recombinant Schizosaccharomyces pombe Mediator of replication checkpoint protein 1 (mrc1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MRC1 ELISA Kit
MRC1 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL014782MO | Mouse Macrophage mannose receptor 1(MRC1) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.156 ng/mL |
MRC1 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09961h | Human mannose receptor,MR ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.039 ng/mL |
