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MOG

MOG,即髓鞘少突胶质细胞糖蛋白,别名BTN6、BTNL11、MGC26137、MOG AluA、MOG AluB等。是一种主要在中枢神经系统少突胶质细胞膜表面及髓鞘最外层表达的蛋白质,属于免疫球蛋白超家族成员之一。MOG抗体相关疾病(MOG-IgG associated disorders, MOGAD)是近年来新认识的免疫介导的中枢神经系统炎性脱髓鞘疾病,与多发性硬化(MS)和视神经脊髓炎谱系疾病(NMOSD)不同,它是一种独立的疾病实体。MOGAD的发病机制可能涉及MOG特异性T滤泡辅助细胞促进B细胞分化,产生大量MOG-IgG,这些抗体进入中枢神经系统后与MOG结合,通过补体和抗体途径介导细胞杀伤作用,导致少突胶质细胞损伤和脱髓鞘。MOGAD的临床表现多样,包括视神经炎、脑膜脑炎、脑干脑炎、脊髓炎等,儿童中较成人更常见,且预后相对较好。

热销产品

Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial (CSB-MP619083HU)

验证数据

CSB-MP619083HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MOG Antibody (CSB-PA619083ESR2HU)

验证数据

CSB-PA619083ESR2HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA619083ESR2HU at dilution of 1:100

CSB-PA619083ESR2HU

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA619083ESR2HU at dilution of 1:100

Human Myelin-oligodendrocyte glycoprotein(MOG) ELISA kit (CSB-EL014709HU)

验证数据

CSB-EL014709HU 标准曲线

货号:CSB-EL014709HU

规格:96T/48T

灵敏度:3.9 pg/mL

检测范围:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

MOG Antibodies

MOG for Homo sapiens (Human)

MOG Proteins

MOG Proteins for Homo sapiens (Human)

MOG ELISA Kit

MOG ELISA Kit for Homo sapiens (Human)