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Il1b

IL1B(白细胞介素1β,Interleukin-1 beta)是一种关键的促炎细胞因子,由多种细胞产生,具有调节炎症反应、免疫调节和组织修复等多种生物学功能。IL1B最初以非活性酶原形式存在,需通过蛋白水解过程转化为活性形式,这一转化通常由炎症小体的效应成分caspases完成。IL1B参与的信号通路主要包括NF-κB信号通路和MAPK信号通路,它通过与其受体IL-1RI结合,启动下游信号传导,导致炎症因子和急性期蛋白的表达。此外,IL1B的成熟形式是通过炎症小体途径激活的,其中pro-IL1β的加工需要caspase-1的激活。IL1B在迅速响应炎症信号后产生和释放,与多种免疫和非免疫细胞的激活、增殖和分化密切相关,是炎症和免疫应答中不可或

热销产品

Recombinant Human Interleukin-1 beta protein (IL1B),Partial (CSB-EP011614HUa0)

验证数据

CSB-EP011614HUa0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Il1b Antibodies

Il1b for Homo sapiens (Human)

Il1b for Sheep

Il1b for Mus musculus (Mouse)

Il1b Proteins

Il1b Proteins for Capra hircus (Goat)

Il1b Proteins for Mus musculus (Mouse)

Il1b Proteins for Oryctolagus cuniculus (Rabbit)

Il1b Proteins for Ovis aries (Sheep)

Il1b Proteins for Sus scrofa (Pig)

Il1b Proteins for Felis catus (Cat) (Felis silvestris catus)

Il1b Proteins for Macaca mulatta (Rhesus macaque)

Il1b Proteins for Bos taurus (Bovine)

Il1b Proteins for Homo sapiens (Human)

Il1b Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Il1b Proteins for Macaca nemestrina (Pig-tailed macaque)

Il1b Proteins for Cervus elaphus (Red deer)

Il1b Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

Il1b Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)

Il1b Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

Il1b Proteins for Equus caballus (Horse)

Il1b Proteins for Phoca hispida (Ringed seal) (Pusa hispida)

Il1b Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

Il1b Proteins for Rattus norvegicus (Rat)

Il1b Proteins for Eumetopias jubatus (Steller sea lion) (Phoca jubata)

Il1b Proteins for Phoca vitulina richardsi (Pacific harbor seal)

Il1b Proteins for Lama glama (Llama)

Il1b Proteins for Delphinapterus leucas (Beluga whale)

Il1b Proteins for Trichosurus vulpecula (Brush-tailed possum)

Il1b Proteins for Cavia porcellus (Guinea pig)

Il1b ELISA Kit

Il1b ELISA Kit for Bos taurus (Bovine)

Il1b ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Il1b ELISA Kit for Guinea Sus scrofa (Pig)

Il1b ELISA Kit for Homo sapiens (Human)

Il1b ELISA Kit for Mus musculus (Mouse)

Il1b ELISA Kit for Sus scrofa (Pig)

Il1b ELISA Kit for Oryctolagus cuniculus (Rabbit)

Il1b ELISA Kit for Rattus norvegicus (Rat)

Il1b ELISA Kit for Ovis aries (Sheep)

Il1b ELISA Kit for Capra hircus (Goat)

Il1b ELISA Kit for Fish