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HLA-G

HLA-G(Human Leukocyte Antigen-G)是人类白细胞抗原(HLA)家族的一员,在免疫调节中扮演重要角色。HLA-G是一种MHC-Ib分子,与MHC-Ia(HLA-A、B、C等)不同,其表达受到严格调控。它具有特定的结构,包括一个α链和β2微球蛋白链,形成HLA-G分子的亚型。HLA-G的主要功能之一是在免疫调节中发挥作用。它能够抑制免疫细胞对特定抗原的识别,调节T细胞的活性,并抑制自身免疫反应,有助于维持胎儿在母体子宫内的免疫耐受性。HLA-G也参与免疫逃避,帮助胎儿和某些肿瘤细胞逃避免疫系统的攻击,从而促进其存活和生长。HLA-G的确切信号通路涉及多种细胞因子和信号分子,但其调节免疫反应和调控细胞免疫逃避的作用机制尚未完全明确。 HLA-G其独特的功能和作用机制使其成为研究的热点,并且可能在未来成为治疗和诊断的重要靶点。

热销产品

Recombinant Human papillomavirus type 16 Protein E6 (E6)

验证数据

SDS-PAGE
CSB-MP010509HU-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS
CSB-MP010509HU LC-MS-1

Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of CSB-MP010509HU could indicate that this peptide derived from Mammalian Cell-expressed Homo sapiens(Human) HLA-G.

LC-MS
CSB-MP010509HU LC-MS-2

Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of CSB-MP010509HU could indicate that this peptide derived from Mammalian Cell-expressed Homo sapiens(Human) HLA-G.


HLA-G Antibodies

HLA-G for Homo sapiens (Human)

HLA-G ELISA Kit

HLA-G ELISA Kit for Homo sapiens (Human)