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FCGR3A

FCGR3A,(Fc fragment of IgG receptor IIIa,也称为CD16a)是一种细胞膜上的Fc受体。它属于Fcγ受体家族中的一员,主要表达在免疫细胞表面,如自然杀伤细胞(NK细胞)和巨噬细胞。其主要功能是通过结合到免疫球蛋白G(IgG)的Fc区域,介导抗体依赖性细胞毒性(ADCC)作用。当特定抗体与靶标细胞表面的抗原结合后,ADCC作用会激活免疫细胞上的FCGR3A,从而促使这些免疫细胞释放毒素和细胞因子,杀伤或破坏靶标细胞。FCGR3A在免疫应答和抗体介导的免疫效应中起着关键作用。其在免疫治疗中的作用日益受到关注。

热销产品

FCGR3A Recombinant Monoclonal Antibody CSB-RA008543MA1HU

验证数据

IF
CSB-RA008543MA1HU IF

Immunofluorescence staining of Hela cell with CSB-RA008543MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

FCGR3A Antibodies

FCGR3A for Homo sapiens (Human)

FCGR3A Proteins

FCGR3A Proteins for Homo sapiens (Human)

FCGR3A Proteins for Bos taurus (Bovine)

FCGR3A Proteins for Macaca mulatta (Rhesus macaque)

FCGR3A Proteins for Sus scrofa (Pig)

FCGR3A Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

FCGR3A ELISA Kit

FCGR3A ELISA Kit for Homo sapiens (Human)