FCGR3A
FCGR3A,(Fc fragment of IgG receptor IIIa,也称为CD16a)是一种细胞膜上的Fc受体。它属于Fcγ受体家族中的一员,主要表达在免疫细胞表面,如自然杀伤细胞(NK细胞)和巨噬细胞。其主要功能是通过结合到免疫球蛋白G(IgG)的Fc区域,介导抗体依赖性细胞毒性(ADCC)作用。当特定抗体与靶标细胞表面的抗原结合后,ADCC作用会激活免疫细胞上的FCGR3A,从而促使这些免疫细胞释放毒素和细胞因子,杀伤或破坏靶标细胞。FCGR3A在免疫应答和抗体介导的免疫效应中起着关键作用。其在免疫治疗中的作用日益受到关注。
热销产品
● FCGR3A Recombinant Monoclonal Antibody CSB-RA008543MA1HU
验证数据
Immunofluorescence staining of Hela cell with CSB-RA008543MA1HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
FCGR3A Antibodies
FCGR3A for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA287660 | FCGR3A Antibody | Human | ELISA,IHC |
CSB-PA183080 | FCGR3A Antibody | Human | ELISA,IHC |
CSB-PA008543LA01HU | FCGR3A Antibody | Human | ELISA, IHC, IF |
CSB-PA008543LB01HU | FCGR3A Antibody, HRP conjugated | Human | ELISA |
CSB-PA008543LC01HU | FCGR3A Antibody, FITC conjugated | Human | |
CSB-PA008543LD01HU | FCGR3A Antibody, Biotin conjugated | Human | ELISA |
CSB-RA008543MA1HU | FCGR3A Recombinant Monoclonal Antibody | Human | ELISA, IF |
FCGR3A Proteins
FCGR3A Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP008543HU1 CSB-EP008543HU1 CSB-BP008543HU1 CSB-MP008543HU1 CSB-EP008543HU1-B |
Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF008543HU | Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A) | in vitro E.coli expression system |
CSB-AP005111HU | Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A), partial (Active) | Mammalian cell |
CSB-EP008543HU2 | Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A), partial | E.coli |
FCGR3A Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP303590BO CSB-EP303590BO CSB-BP303590BO CSB-MP303590BO CSB-EP303590BO-B |
Recombinant Bovine Low affinity immunoglobulin gamma Fc region receptor III (FCGR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FCGR3A Proteins for Macaca mulatta (Rhesus macaque)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP388701MOW CSB-EP388701MOW CSB-BP388701MOW CSB-MP388701MOW CSB-EP388701MOW-B |
Recombinant Macaca mulatta Low affinity immunoglobulin gamma Fc region receptor III (FCGR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FCGR3A Proteins for Sus scrofa (Pig)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP636747PI CSB-EP636747PI CSB-BP636747PI CSB-MP636747PI CSB-EP636747PI-B |
Recombinant Pig Low affinity immunoglobulin gamma Fc region receptor III (FCGR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FCGR3A Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP854680MOV CSB-EP854680MOV CSB-BP854680MOV CSB-MP854680MOV CSB-EP854680MOV-B |
Recombinant Macaca fascicularis Low affinity immunoglobulin gamma Fc region receptor III (FCGR3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FCGR3A ELISA Kit
FCGR3A ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL008543HU | Human Low affinity immunoglobulin gamma Fc region receptor III-A(FCGR3A) ELISA kit | serum, plasma, tissue homogenates | 11.75 pg/mL |