FABP5
FABP5,即脂肪酸结合蛋白5,是一种广泛存在于多种组织中的脂质伴侣蛋白。它参与调控脂肪酸的摄取、转运、代谢以及炎症反应等多种生物学过程。FABP5的作用机制涉及与长链不饱和脂肪酸的结合,进而影响细胞内的脂质代谢和信号传导。特别是在氧化应激状态下,FABP5可以通过谷胱甘肽化修饰,促进其核转位,激活PPARβ/δ信号通路,抑制巨噬细胞炎症,对急性肺损伤等炎症性疾病具有保护作用。此外,FABP5还通过调节PPARγ信号通路影响巨噬细胞的M2极化,进而参与过敏性哮喘等免疫调节过程。FABP5的功能异常与多种疾病包括癌症、炎症性疾病和代谢性疾病等有关,是重要的疾病治疗靶点。
热销产品
Recombinant Human Fatty acid-binding protein 5 (FABP5) (CSB-EP007946HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Fatty acid-binding protein, epidermal(FABP5) ELISA kit (CSB-EL007946HU)
验证数据
货号:CSB-EL007946HU
规格:96T/48T
灵敏度:0.195 ng/mL
检测范围:0.78 ng/mL-50 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
FABP5 Antibodies
FABP5 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA007946GA01HU | FABP5 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA007946ESR1HU | FABP5 Antibody | Human | ELISA, WB |
FABP5 Proteins
FABP5 Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP007946RA CSB-EP007946RA CSB-BP007946RA CSB-MP007946RA CSB-EP007946RA-B |
Recombinant Rat Fatty acid-binding protein, epidermal (Fabp5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FABP5 Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP007946BO CSB-EP007946BO CSB-BP007946BO CSB-MP007946BO CSB-EP007946BO-B |
Recombinant Bovine Fatty acid-binding protein, epidermal (FABP5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FABP5 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-EP007946HUe0 | Recombinant Human Fatty acid-binding protein (FABP5) | E.coli |
CSB-EP007946HU | Recombinant Human Fatty acid-binding protein 5 (FABP5) | E.coli |
FABP5 ELISA Kit
FABP5 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL007946HU | Human Fatty acid-binding protein, epidermal(FABP5) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.195 ng/mL |