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Dlat

DLAT(dihydrolipoamide S-acetyltransferase)是线粒体中的蛋白质,是α-酮戊二酸脱氢酶复合物的组成部分之一。它包含活性位点,能够催化乙酰辅酶A和α-酮戊二酸之间的乙酰转移反应。 DLAT在三羧酸循环(TCA循环)中发挥重要作用,促进食物分解产生的乙酰辅酶A与三羧酸循环中产生的α-酮戊二酸之间的关键代谢步骤。能够将乙酰辅酶A转移至α-酮戊二酸,促进其进入TCA循环,从而参与产生细胞能量所需的NADH和FADH2。DLAT的活性和功能对于维持正常的能量代谢过程至关重要,特别是在细胞的线粒体内。了解DLAT在能量代谢中的作用对于理解线粒体功能异常和相关疾病(如代谢性疾病)的发生具有重要意义。

热销产品

Recombinant Mouse Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (Dlat)

验证数据

SDS-PAGE
CSB-EP804374MOa0-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS
CSB-EP804374MOa0 LC-MS-1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP804374MOa0 could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Dlat.

LC-MS
CSB-EP804374MOa0 LC-MS-2

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP804374MOa0 could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Dlat.


Dlat Antibodies

Dlat for Homo sapiens (Human)