CEACAM8
CEACAM8,作为人类颗粒介质CEA家族的重要成员,是一种具有独特结构特点的跨膜糖蛋白。它主要由跨膜区域和糖基化的胞外区域组成,包括N端的可变Ig结构域和恒定的Ig结构域,这种结构使得CEACAM8能与其他分子特异性结合,参与多种生物过程。在功能上,CEACAM8在炎症反应和免疫调节中扮演关键角色,通过影响白细胞的黏附、迁移和细胞间信号传导来调节免疫反应。虽然CEACAM8的具体信号通路尚不完全清楚,但可以推测它可能通过与其他细胞表面受体或配体的相互作用触发信号级联反应,从而影响细胞的生物学行为。此外,CEACAM8的表达水平在某些疾病状态下会发生变化,因此研究其结构、功能和信号通路对于理解疾病机制和寻找新疗法具有重要意义。通过深入研究CEACAM8,科学家们有望为相关疾病的诊断和治疗提供新的思路和方法。
热销产品
● Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) (Active)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM8 at 2μg/mL can bind Anti-CEACAM8 recombinant antibody (CSB-RA005168MA1HU),the EC50 is 19.38-21.68 ng/mL.
● Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) ELISA kit
验证数据
货号:CSB-EL005168HU
规格:96T,5×96T,10×96T
灵敏度:0.156 ng/mL
检测范围:0.625 ng/mL-40 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CEACAM8 Antibodies
CEACAM8 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA005168ESR2HU | CEACAM8 Antibody | Human | ELISA, IHC |
CSB-PA077200 | CEACAM8 Antibody | Human | ELISA,IHC |
CSB-RA937940A0HU | CEACAM8 Recombinant Monoclonal Antibody | Human | ELISA, FC |
CSB-RA005168MA1HU | CEACAM8 Recombinant Monoclonal Antibody | Human | ELISA |
CEACAM8 Proteins
CEACAM8 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP005168HU CSB-BP005168HU CSB-EP005168HU-B |
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
CSB-EP005168HU | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) | E.coli |
CSB-MP005168HU | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) (Active) | Mammalian cell |
CEACAM8 ELISA Kit
CEACAM8 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL005168HU | Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.156 ng/mL |