CD79A
CD79a，即B细胞抗原受体复合体α链，别名MB-1。它是一种与B细胞抗原受体(BCR)相关的膜糖蛋白，由CD79a和CD79b两种异二聚体亚单位组成。CD79a在B细胞的各个发育阶段均有表达，是B细胞的特征性标记之一。CD79a的作用机制主要是与CD79b共同参与B细胞受体的信号转导。当抗原与BCR结合后，CD79a/CD79b异二聚体能够传递激活信号，引发B细胞的增殖、分化和抗体产生。CD79a的细胞质区含有免疫受体酪氨酸激活基序(ITAM)，是信号转导的关键结构。CD79a还参与调节B细胞的凋亡和耐受。CD79a在生物学上的意义主要体现在其对B细胞功能的重要调控作用。作为B细胞受体的重要组成部分，CD79a参与B细胞的抗原识别、激活、增殖和分化等过程。此外，CD79a的表达还与某些B细胞肿瘤的发生发展相关，如B细胞急性淋巴细胞性白血病(B-ALL)等。因此，CD79a是B细胞生物学研究和B细胞相关疾病治疗的重要靶点。
热销产品
CD79A Antibody (CSB-PA004957LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004957LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA004957LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA004957LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
CD79A Antibodies
CD79A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA165334 | CD79A Antibody | Human | ELISA,WB |
| CSB-PA080055 | CD79A Antibody | Human | WB, ELISA |
| CSB-PA080056 | CD79A Antibody | Human,Mouse | WB, ELISA |
| CSB-PA780889 | CD79A Antibody | Human,Mouse | ELISA,WB |
| CSB-PA183306 | CD79A Antibody | Human,Mouse | ELISA,WB |
| CSB-PA004957LA01HU | CD79A Antibody | Human | ELISA, IHC, IF |
| CSB-PA004957LB01HU | CD79A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA004957LC01HU | CD79A Antibody, FITC conjugated | Human | |
| CSB-MA961575 | CD79A Monoclonal Antibody | Human | ELISA, IHC |
CD79A Proteins
CD79A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957DO1 CSB-EP004957DO1 CSB-BP004957DO1 CSB-MP004957DO1 CSB-EP004957DO1-B |
Recombinant Dog B-cell antigen receptor complex-associated protein alpha chain (CD79A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957DO | Recombinant Dog B-cell antigen receptor complex-associated protein alpha chain (CD79A) | in vitro E.coli expression system |
CD79A Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957MO1 CSB-EP004957MO1 CSB-BP004957MO1 CSB-MP004957MO1 CSB-EP004957MO1-B |
Recombinant Mouse B-cell antigen receptor complex-associated protein alpha chain (Cd79a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957MO | Recombinant Mouse B-cell antigen receptor complex-associated protein alpha chain (Cd79a) | in vitro E.coli expression system |
CD79A Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957HU1 CSB-EP004957HU1 CSB-BP004957HU1 CSB-MP004957HU1 CSB-EP004957HU1-B |
Recombinant Human B-cell antigen receptor complex-associated protein alpha chain (CD79A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957HU | Recombinant Human B-cell antigen receptor complex-associated protein alpha chain (CD79A) | in vitro E.coli expression system |
CD79A Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004957BO1 CSB-EP004957BO1 CSB-BP004957BO1 CSB-MP004957BO1 CSB-EP004957BO1-B |
Recombinant Bovine B-cell antigen receptor complex-associated protein alpha chain (CD79A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004957BO | Recombinant Bovine B-cell antigen receptor complex-associated protein alpha chain (CD79A) | in vitro E.coli expression system |
