CD6
CD6是一种关键的1型跨膜糖蛋白，其细胞外部分包含三个富含半胱氨酸的清道夫受体结构域，高度糖基化，并与免疫球蛋白超家族分子CD166（ALCAM）作为其主要配体相互作用。当CD6与ALCAM结合时，会激活与T细胞活化、增殖、分化和存活相关的丝裂原活化蛋白激酶通路。这一相互作用在维持免疫平衡、调节T细胞功能及转运中起到重要作用。研究表明，通过阻断CD6-ALCAM通路，可以抑制致病性T细胞的激活和转运，为相关疾病的治疗提供了新的策略。此外，CD6还涉及胸腺细胞与基质细胞的相互作用以及自身免疫和移植物抗宿主病等过程。
热销产品
验证数据
All lanes: CD6 antibody at 4μg/ml
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: HT-29 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 72, 69, 64, 65, 59, 61 kDa
Observed band size: 72 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA326953ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human thymus tissue using CSB-PA326953ESR1HU at dilution of 1:100
CD6 Antibodies
CD6 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA134350 | CD6 Antibody | Human | ELISA,WB |
| CSB-PA326953ESR1HU | CD6 Antibody | Human | ELISA, WB, IHC |
| CSB-PA326953ESR2HU | CD6 Antibody | Human | ELISA, IHC |
| CSB-PA006156 | CD6 Antibody | Human | WB, ELISA |
| CSB-PA070265 | CD6 Antibody | Human | WB, ELISA |
CD6 Proteins
CD6 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP326953HU1 CSB-EP326953HU1 CSB-BP326953HU1 CSB-MP326953HU1 CSB-EP326953HU1-B |
Recombinant Human T-cell differentiation antigen CD6 (CD6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
