CD40
CD40（又称为Bp50）是一种细胞表面蛋白质，属于肿瘤坏死因子受体超家族（TNF receptor superfamily）的成员之一，CD40是一种单链型跨膜蛋白，包括一个胞外区域、一个跨膜区域和一个胞浆区域。它的胞外区域可以与其配体CD40L（CD40配体）结合，触发信号传导。CD40是免疫系统中的关键调节分子，对于体液免疫应答、免疫记忆的形成以及免疫调节都具有重要意义。它的功能扩展到B细胞激活、抗原呈递和炎症调节等多个层面，因此对于理解免疫系统如何应对感染、自身免疫疾病以及癌症等疾病的研究具有重要价值。此外，CD40信号传导也在免疫治疗研究中被广泛研究，以开发新的治疗方法来增强或抑制免疫系统的特定响应。
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验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized CD40 at 2 μg/ml can bind CD40L (CSB-MP004937HU3), the EC50 is 3.112-3.858 ng/ml.
Activity: Human CD40 protein hFc tag (CSB-MP004936HU1) captured on COOH chip can bind Human CD40L protein hFc and Flag tag (CSB-MP004937HU3) with an affinity constant of 2.06 nM as detected by LSPR Assay.
CD40 Antibodies
CD40 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004936GA01HU | CD40 Antibody | Human | ELISA,WB |
| CSB-PA176134 | Phospho-CD40 (Thr254) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA001455 | CD40 Antibody | Human,Mouse,Monkey | WB, IHC, ELISA |
| CSB-PA080031 | Phospho-CD40 (T254) Antibody | Human,Mouse | WB, ELISA |
| CSB-PA215588 | CD40 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA004936LA01HU | CD40 Antibody | Human, Mouse | ELISA, WB, IF |
| CSB-PA004936LB01HU | CD40 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA004936LC01HU | CD40 Antibody, FITC conjugated | Human | |
| CSB-PA004936LD01HU | CD40 Antibody, Biotin conjugated | Human | ELISA |
CD40 Proteins
CD40 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004936MO1 CSB-EP004936MO1 CSB-BP004936MO1 CSB-MP004936MO1 CSB-EP004936MO1-B |
Recombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004936MO | Recombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40) | in vitro E.coli expression system |
CD40 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004936HU1 CSB-EP004936HU1 CSB-EP004936HU1-B |
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial | Yeast E.coli In Vivo Biotinylation in E.coli |
| CSB-CF004936HU | Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40) | in vitro E.coli expression system |
| CSB-AP005171HU | Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) | Mammalian cell |
| CSB-AP005181HU | Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) | Mammalian cell |
| CSB-MP004936HU1 | Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) | Mammalian cell |
CD40 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP636713BO CSB-EP636713BO CSB-BP636713BO CSB-MP636713BO CSB-EP636713BO-B |
Recombinant Bovine Tumor necrosis factor receptor superfamily member 5 (CD40), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD40 Proteins for Callithrix jacchus (White-tufted-ear marmoset)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP659466CYL CSB-EP659466CYL CSB-BP659466CYL CSB-MP659466CYL CSB-EP659466CYL-B |
Recombinant Callithrix jacchus Tumor necrosis factor receptor superfamily member 5 (CD40), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD40 Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP675871HO CSB-EP675871HO CSB-BP675871HO CSB-MP675871HO CSB-EP675871HO-B |
Recombinant Horse Tumor necrosis factor receptor superfamily member 5 (CD40), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD40 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP767175DO CSB-EP767175DO CSB-BP767175DO CSB-MP767175DO CSB-EP767175DO-B |
Recombinant Dog Tumor necrosis factor receptor superfamily member 5 (CD40), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD40 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-BP851448PI CSB-MP851448PI CSB-EP851448PI-B |
Recombinant Pig Tumor necrosis factor receptor superfamily member 5 (CD40), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD40 ELISA Kit
CD40 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL004936MO | Mouse Tumor necrosis factor receptor superfamily member 5(CD40) ELISA kit | 7.8 pg/ml |
