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CADM1

CADM1(Cell Adhesion Molecule 1)也被称为SynCAM1(Synaptic Cell Adhesion Molecule 1);参与多种生物学过程和疾病发生发展。 ADM1的胞外结构域包括一个N-末端信号序列、三个Ig-like结构域和一个C-末端结构域,其中第一个Ig-like结构域参与了细胞间的黏附和信号转导。CADM1的细胞内结构域包括一个短的胞内区域和一个长的胞内区域,前者含有一个肽键酶切位点和几个磷酸化位点,后者则包含多个蛋白质相互作用位点和信号调节结构域 它在神经元、免疫细胞、肿瘤等细胞中表达,并通过其胞外结构域和细胞内信号通路影响细胞间的黏附、迁移、增殖和凋亡等生物学行为。

更多相关阅读:CADM1/TSLC1:免疫球蛋白超家族黏附分子,一种新的TSG肿瘤抑制基因!

热销产品

Recombinant Mouse Cell adhesion molecule 1(Cadm1),partial (Active) CSB-MP004425MO

验证数据

High Purity Validated by SDS-PAGE
CSB-MP004425MO SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA
CSB-MP004425MO AC

Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse CADM1 at 2μg/mL can bind Mouse CRTAM (CSB-MP614820MO), the EC50 is 52.61-92.92 ng/mL. 

CADM1 Antibodies

CADM1 for Homo sapiens (Human)

CADM1 Proteins

CADM1 Proteins for Mus musculus (Mouse)

CADM1 Proteins for Homo sapiens (Human)