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Bcl11a

BCL11A,全称为B-cell CLL/lymphoma 11A,是一种锌指蛋白,属于转录因子家族成员。它在多种细胞类型中表达,包括髓系和B细胞,可能在白血病发生和造血过程中扮演重要角色。BCL11A基因位于染色体2p15,其编码的蛋白通过结合DNA上的特定序列,调控下游基因的表达。BCL11A在淋巴细胞的形成中起着关键作用,特别是在胎儿肝脏中B细胞的形成。此外,BCL11A还可能作为白血病分子治疗的新靶标,其异常表达与白血病的发生发展有关。因此,BCL11A在细胞发育、白血病的发生以及潜在的治疗策略中具有重要的生物学意义。

热销产品

BCL11A Antibody

验证数据

IHC
CSB-PA872429ESR1HU IHC-1

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA872429ESR1HU at dilution of 1:100

IHC
CSB-PA872429ESR1HU IHC-2

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA872429ESR1HU at dilution of 1:100

IHC
CSB-PA872429ESR1HU IHC-3

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA872429ESR1HU at dilution of 1:100


Bcl11a Antibodies

Bcl11a for Homo sapiens (Human)

Bcl11a Proteins

Bcl11a Proteins for Homo sapiens (Human)