BSG

Basigin（BSG），又称CD147，是一种高度糖基化的、分子量为50～60kD的跨膜糖蛋白，属于免疫球蛋白超家族（IgSF）成员。人BASIGIN由269个氨基酸组成，可分为胞外区、跨膜区及胞内区。BSG可通过刺激肿瘤细胞自身及其周围的成纤维细胞，分泌多种基质金属蛋白酶(extracellular matrix metalloproteinase，MMP)，包括MMP-1、MMP-2、MMP-3、MMP-11以及MT1-MMP和MT2-MMP等，从而加快肿瘤周围基质的降解，促进了肿瘤的转移。已证实BASIGIN在许多类型的人实体瘤，如肺癌、肝癌、宫颈癌、结肠癌、乳腺癌、卵巢癌、食管癌或胃癌中过度表达。既往研究表明，Basigin分子是肿瘤发展过程重要的功能性膜蛋白，参与多种与癌症有关的现象。目前，Basigin已被作为一种新的肿瘤标志物和治疗靶点。

Recombinant Human BSG 活性蛋白实验验证数据

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized CD147 at 2 μg/ml can bind Anti-CD147 recombinant Antibody, the EC₅₀ is 21.95-33.12 ng/ml.

BSG Antibody

BSG Protein

BSG ELISA Kit

BSG Antibodies

BSG for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA11759A0Rb	BSG Antibody	Human	ELISA, WB, IHC
CSB-PA11759C0Rb	BSG Antibody, FITC conjugated	Human
CSB-PA002831GA01HU	BSG Antibody	Human	ELISA,WB,IHC
CSB-PA11759B0Rb	BSG Antibody, HRP conjugated	Human	ELISA
CSB-PA11759D0Rb	BSG Antibody, Biotin conjugated	Human	ELISA
CSB-PA002331	BSG Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA005853	BSG Antibody	Human	WB, ELISA
CSB-PA993569	BSG Antibody	Human	ELISA,IHC
CSB-PA570608	BSG Antibody	Human	ELISA,WB,IHC

BSG Proteins

BSG Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP002831MO1 CSB-EP002831MO1 CSB-BP002831MO1 CSB-MP002831MO1 CSB-EP002831MO1-B	Recombinant Mouse Basigin (Bsg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF002831MO	Recombinant Mouse Basigin (Bsg)	in vitro E.coli expression system

BSG Proteins for Gallus gallus (Chicken)

产品货号	产品名称	来源
CSB-YP002831CH1 CSB-EP002831CH1 CSB-BP002831CH1 CSB-MP002831CH1 CSB-EP002831CH1-B	Recombinant Chicken Basigin (BSG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF002831CH	Recombinant Chicken Basigin (BSG)	in vitro E.coli expression system

BSG Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP002831HU CSB-EP002831HU CSB-BP002831HU CSB-EP002831HU-B	Recombinant Human Basigin (BSG), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-RP117574h	Recombinant Human Basigin (BSG), partial	E.coli
CSB-CF002831HU	Recombinant Human Basigin (BSG)	in vitro E.coli expression system
CSB-MP002831HU	Recombinant Human Basigin (BSG), partial	Mammalian cell
CSB-MP002831HUf3	Recombinant Human Basigin (BSG), partial	Mammalian cell
CSB-MP002831HU1	Recombinant Human Basigin (BSG), partial (Active)	Mammalian cell

BSG Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP002831RA1 CSB-EP002831RA1 CSB-BP002831RA1 CSB-MP002831RA1 CSB-EP002831RA1-B	Recombinant Rat Basigin (Bsg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF002831RA	Recombinant Rat Basigin (Bsg)	in vitro E.coli expression system

BSG Proteins for Oryctolagus cuniculus (Rabbit)

产品货号	产品名称	来源
CSB-YP631727RB CSB-EP631727RB CSB-BP631727RB CSB-MP631727RB CSB-EP631727RB-B	Recombinant Rabbit Basigin (BSG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BSG Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP771275BO CSB-EP771275BO CSB-BP771275BO CSB-MP771275BO CSB-EP771275BO-B	Recombinant Bovine Basigin (BSG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BSG Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

产品货号	产品名称	来源
CSB-YP857519DXU CSB-EP857519DXU CSB-BP857519DXU CSB-MP857519DXU CSB-EP857519DXU-B	Recombinant Cricetulus griseus Basigin (BSG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli