ASPA
ASPA,即天冬氨酸酶,它是一种在生物体内具有多种功能的蛋白质 。ASPA由日本国际热传导株式会社的研究人员于1975年发现,分子量为21.1 kDa,由两个等量的多肽链组成,包含10个氨基酸 。它在细胞内参与促进细胞增殖、诱导细胞凋亡、调节细胞周期和参与细胞信号传递等多种生物学过程 。在肿瘤研究中,ASPA被用作药物靶点,能够与肿瘤细胞中的蛋白质相互作用,抑制肿瘤细胞的生长和扩散 。ASPA在药物发现中具有广泛的应用,可以作为治疗癌症的药物靶点,例如抑制ASPA活性的药物可以抑制癌细胞的生长和扩散 。此外,ASPA还可以作为生物标志物,用于检测疾病的程度和治疗效果 。在生物学意义上,ASPA的活性和表达水平与多种疾病的发生发展密切相关,是医学研究和治疗中的一个重要靶点。
热销产品
Recombinant Human Aspartoacylase (ASPA) (CSB-YP002223HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA790667(ASPA Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA790667(ASPA Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse kidney tissue, human fetal kidney tissue, Primary antibody: CSB-PA790667(ASPA Antibody) at dilution 1/1400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
ASPA Antibodies
ASPA for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA002223GA01HU | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA790667 | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA075666 | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
ASPA Proteins
ASPA Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP002223HU | Recombinant Human Aspartoacylase (ASPA) | Yeast |
CSB-EP002223HU | Recombinant Human Aspartoacylase (ASPA) | E.coli |
CSB-BP002223HU | Recombinant Human Aspartoacylase (ASPA) | Baculovirus |
CSB-MP002223HU | Recombinant Human Aspartoacylase (ASPA) | Mammalian cell |