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TBKBP1 Antibody

  • 中文名称：
    TBKBP1兔多克隆抗体
  • 货号：
    CSB-PA023233LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of Hela cells with CSB-PA023233LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TBKBP1 Polyclonal antibody
  • Uniprot No.：
    A7MCY6
  • 基因名：
  • 别名：
    KIAA0775 antibody; ProSAPiP2 antibody; SINTBAD antibody; TANK binding kinase 1 binding protein 1 antibody; TANK-binding kinase 1-binding protein 1 antibody; TBK1 binding protein 1 antibody; TBK1-binding protein 1 antibody; TBKB1_HUMAN antibody; Tbkbp1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human TANK-binding kinase 1-binding protein 1 protein (327-427AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TBKBP1 Antibody (CSB-PA023233LA01HU)，的标记方式是Non-conjugated。对于TBKBP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023233LB01HU TBKBP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA023233LC01HU TBKBP1 Antibody, FITC conjugated
    Biotin CSB-PA023233LD01HU TBKBP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
  • 基因功能参考文献：
    1. The two selected single nucleotide polymorphisms (SNPs) in TBKBP1 show no relationship with the clinical outcomes. None of the 12 SNPs is related to mSASSS. PMID: 25494292
    2. TBKBP1 is associated with the severity of ankylosing spondylitis in the Chinese Han population PMID: 23637848
    3. Studies show that three proteins expressed in HEK-293T cells (NAP1, TANK and TBKBP1) interact with TBK1. PMID: 23286385
    4. results suggest that efficient signal transduction upon viral infection requires SINTBAD, TANK and NAP1 because they link TBK1 and IKKi to virus-activated signalling cascades PMID: 17568778
  • 组织特异性：
    Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
  • 数据库链接：

    HGNC: 30140

    OMIM: 608476

    KEGG: hsa:9755

    STRING: 9606.ENSP00000354777

    UniGene: Hs.94790