AASS Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) AASS Polyclonal antibody
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Uniprot No.:Q9UDR5
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基因名:
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别名:AASSAlpha-aminoadipic semialdehyde synthase antibody; mitochondrial antibody; LKR/SDH) [Includes: Lysine ketoglutarate reductase antibody; LKR antibody; LOR antibody; EC 1.5.1.8); Saccharopine dehydrogenase antibody; SDH antibody; EC 1.5.1.9)] antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Alpha-aminoadipic semialdehyde synthase, mitochondrial protein (224-364AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,AASS Antibody (CSB-PA883373LA01HU),的标记方式是Non-conjugated。对于AASS Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, WB, IHC
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:5000 IHC 1:200-1:500 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
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基因功能参考文献:
- GR and KLF15 physically interact via low affinity GR binding sites within glucocorticoid response elements (GREs) for PRODH and AASS that contribute to combinatorial regulation with KLF15. PMID: 26088140
- Mitochondrial NADPH is crucial for AASS function PMID: 24847004
- Hyperlysinemia is caused by mutations in AASS PMID: 23570448
- Isolation and characterization of the mouse ortholog. PMID: 10567240
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相关疾病:Hyperlysinemia, 1 (HYPLYS1); 2,4-dienoyl-CoA reductase deficiency (DECRD)
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亚细胞定位:Mitochondrion.
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蛋白家族:AlaDH/PNT family; Saccharopine dehydrogenase family
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组织特异性:Expressed in all 16 tissues examined with highest expression in the liver.
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数据库链接:
HGNC: 17366
OMIM: 238700
KEGG: hsa:10157
STRING: 9606.ENSP00000377040
UniGene: Hs.156738