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  4. Recombinant Rat Transmembrane protein 109 (Tmem109)

Recombinant Rat Transmembrane protein 109 (Tmem109)

  • 货号：
    CSB-CF023678RA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Tmem109
  • Uniprot No.：
  • 别名：
    Tmem109; Transmembrane protein 109; Mitsugumin-23; Mg23
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    34-243
  • 氨基酸序列
    QTHREFASPGQQKRESSADILTEIGRSLKETLDTWLGPETMHVISETLLQVMWAISSAIS VACFALSGIAAQLLSALGLDGEQLTQVLKLSPSQVQTLLLWGAAALVIYWLLSLLLGLVL ALLGRILGGLKLVLFVAGFVGLVRSVPDPSTRALLLLALLTVFALLSRLTGSRSSGTHLE AKVRGLERQIEELRGRQRRAAKIPRSMEEE
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro.
  • 基因功能参考文献：
    1. Data, including data from studies in vesicles of knockout mice, suggest pathophysiological levels of Zn2+ (>2nM) cause dysregulation of RyR2 opening; in sarcoplasmic reticulum, RyR2 are not the only Ca2+-channels regulated by Zn2+; in cardiomyocytes exposed to ischemic/hypoxic conditions, intracellular Zn2+ levels are elevated, coinciding with increased MG23 expression. (RyR2 = ryanodine receptor 2; MG23 = mitsugumin 23) PMID: 28630041
  • 亚细胞定位：
    Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
  • 数据库链接：

    KEGG: rno:361732

    STRING: 10116.ENSRNOP00000036054

    UniGene: Rn.1105