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  4. Recombinant Pongo pygmaeus G-protein coupled receptor 56 (GPR56)

Recombinant Pongo pygmaeus G-protein coupled receptor 56 (GPR56)

  • 货号：
    CSB-CF703516EXP
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    ADGRG1; GPR56; Adhesion G-protein coupled receptor G1; G-protein coupled receptor 56
  • 种属：
    Pongo pygmaeus (Bornean orangutan)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-687
  • 氨基酸序列
    RGHREDFRFCSQRNQTHKSSLHYKATQDLRISIENSEEALTVHAPFPAAHPASQSFPDPR GLYHFCLYWNRHAGRLHLLYGKHDFLLSDKASSLLCFQHQEESLAQGPPLLATSVTSWWS PQNISLPSAASFTFSFHSPSHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRPSAAPA SQQLQSLESKLTSVRFMGDTVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEILEY SVLLPRTLFQRTKGRRGEAEKRLLLVDFSSQALFQDKNASQVLGEKVLGIVVQNTKVANL TEPVVLTFQHQLQPKNVTLQCVFWVEDPTLSSPGHWSSAGCETVRRETQTSCFCNHLTYF AVLMVSSVEVDAVHKHYLSLLSYVGCVISALACVVTIAAYLCSRRKPRDYTIKVHMNLLL AVFLLDMSFLLSEPVALTGSEAGCRAGAIFLHFSLLACLSWMGLEGYNLYRLVVEVFGTY VPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPESVIYPSMCWIRDSLVSY VTNLGLFSLVFLFNMAMLGTMVVQILRLRPHTQKWSHVLTLLGLSLVLGLPWALIFFSFA SGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQARGGPSPLKSNSDSARLPISSGSTSSS RI
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche. Plays an essential role in testis development. Plays a critical role in tumourigenesis.
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.; [ADGRG1 N-terminal fragment]: Secreted.; [ADGRG1 C-terminal fragment]: Membrane raft.
  • 蛋白家族：
    G-protein coupled receptor 2 family, LN-TM7 subfamily