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  4. Recombinant Pig Nociceptin receptor (OPRL1)

Recombinant Pig Nociceptin receptor (OPRL1)

  • 货号：
    CSB-CF016360PI
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    OPRL1; Nociceptin receptor; K3 opiate receptor; Kappa-type 3 opioid receptor; KOR-3; ORGC; Orphanin FQ receptor
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-370
  • 氨基酸序列
    MESLFPAPFWEVLYGSPLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTAVLLTLPFQGTDVLLGFWPFGN ALCKAVIAIDYYNMFTSAFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASI VGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAVCIFLFSFVIPVLIISVCYSLMVR RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAV LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCAPTRRREMQVSDRVRSIAKDVALAC KTSETVPRPA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Detected in brain cortex, stomach, ileum, jejunum and colon.
  • 数据库链接：

    KEGG: ssc:397364

    UniGene: Ssc.16086