Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 跨膜蛋白
  4. Recombinant Mouse Probable G-protein coupled receptor 88 (Gpr88)

Recombinant Mouse Probable G-protein coupled receptor 88 (Gpr88)

  • 货号：
    CSB-CF887640MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    Gpr88; Strg; Probable G-protein coupled receptor 88; Striatum-specific G-protein coupled receptor
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-384
  • 氨基酸序列
    MTNSSSTSTSTTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPSGSAEPPGDWDGGGGSYRLLRGGLL GLGLTVSLLSHCLVALNRYLLITRAPATYQVLYQRRHTVGMLALSWALALGLVLLLPPWA PKPGAEPPQVHYPALLAAGALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC AAAAAAFPAAPHAPGPGGAAHPAQPQPLPAALQPRRAQRRLSGLSVLLLCCVFLLATQPL VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA AAAATAVPAMSQAQLGTRAAGQHW
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function.
  • 基因功能参考文献：
    1. GPR88 in A2A receptor-expressing neurons modulates psychomotor behavior but not sensorimotor gating. PMID: 28700108
    2. GPR88 activity shapes the mouse brain functional and structural connectome PMID: 28882062
    3. Analysis of Gpr88-adenosine A2AR-Cre transgenic mice shows that GPR88 in adenosine A2AR medium spiny neurons regulates locomotor and anxiety behaviors. PMID: 27570825
    4. GPR88 expression in the corpus striatum is necessary to efficiently integrate effort and choice behavior. PMID: 28729439
    5. Results demonstrate that GPR88 is implicated in a large repertoire of behavioral responses that engage motor activity, spatial learning, and emotional processing, reveal functional antagonism between GPR88 and delta opioid receptor activities in vivo PMID: 26188600
    6. This study demonistrated that lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors PMID: 23064379
    7. The modulatory role of Gpr88 in striatal dopamine function suggests it may be a new target for treatments for psychiatric disorders. PMID: 19796684

    显示更多

    收起更多

  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Expressed predominantly in the striatum.
  • 数据库链接：

    KEGG: mmu:64378

    STRING: 10090.ENSMUSP00000087959

    UniGene: Mm.40025