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  4. Recombinant Mouse G-protein coupled receptor 151 protein (Gpr151)

Recombinant Mouse G-protein coupled receptor 151 protein (Gpr151)

  • 货号：
    CSB-CF763191MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    Gpr151; Pgr7; G-protein coupled receptor 151 protein; G-protein coupled receptor PGR7; GPCR-2037
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-422
  • 氨基酸序列
    MGKAMLRAGFADTNSSNMNESFARLHFAGGYLPSDSKDWRTIIPSLLMAVCLVGLVGNLC VIGILLHGVWKRKPSTIHSLILNLSLADFSLLLFSAPVRAAAYSKGVWDLGWFICKSSDW FTHVCMAAKSLTFVVVAKACFAYASDPAKQESIHSRTIWSVLAGIWVVASLLPLPEWLFS TTRRHAGVEMCLVDVPAVAEEFMSMFGKLYPLLVFCLPLLLAGVYFWRAYDQCKTRCTKT RNLRDQMRSKQLTVMLLSTAIISALLWLPEWIAWLWVWHVKAGGPMPPQGFIALSQVLMF FTSTANPLIFLVMSEEFKAGLKGLWKWMITRKPAVTSEVQEAPAGNTEALPGKAPSPETQ TCILDTDGRGSPDDSKEKSGKVVAPILPDVEQFWHERDAVPSAQDNDPIPWEHEGQETEG CN
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Proton-sensing G-protein coupled receptor.
  • 基因功能参考文献：
    1. Study presents a map of the afferent connectivity of a diencephalic neuronal population defined by Gpr151 expression. The connectivity of thalamic versus habenular Gpr151-expressing neurons differed substantially, indicating a neuroanatomical heterogeneity within the Gpr151-system. PMID: 28657115
    2. Gpr151 mRNA in the DRG is elevated a model of neuropathic pain. Pain-related behaviour is unchanged is Gpr151 mutants. PMID: 27913310
    3. This study demonstrated that GPR151 expression in the mouse brain is restricted to habenular neurons projecting to the interpeduncular nucleus,Rostromedial tegmental nucleus, rhabdoid nucleus, mesencephalic raphe nuclei, and dorsal tegmental nucleus. PMID: 25116430
    4. Galanin-receptor like (GalRL) expression is found in the dorsal thalamus; hybridization signals are detected in the striatum, the locus coeruleus, and several hindbrain nuclei. PMID: 15111018
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 组织特异性：
    High expression in the brain and lower levels in kidney and liver. In the nervous system expressed specifically in the habenular area (at protein level).
  • 数据库链接：

    KEGG: mmu:240239

    STRING: 10090.ENSMUSP00000058887

    UniGene: Mm.186779