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  4. Recombinant Mouse Mucin-13 (Muc13)

Recombinant Mouse Mucin-13 (Muc13)

  • 货号：
    CSB-CF015217MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    Muc13; Ly64; Mucin-13; MUC-13; Cell surface antigen 114/A10; Lymphocyte antigen 64
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    18-573
  • 氨基酸序列
    SSSQASSTTSSSGGTSPPTTVQSQSPGSSSQASTTTSSSGGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTVQSQSPGSSSQASTTTSSSGGASPPTTVQSQSPGSSSQVSTTTSSSGGASPPTTVQSQSPGSSSQPGPTQPSGGASSSTVPSGGSTGPSDLCNPNPCKGTASCVKLHSKHFCLCLEGYYYNSSLSSCVKGTTFPGDISMSVSETANLEDENSVGYQELYNSVTDFFETTFNKTDYGQTVIIKVSTAPSRSARSAMRDATKDVSVSVVNIFGADTKETEKSVSSAIETAIKTSGNVKDYVSINLCDHYGCVGNDSSKCQDILQCTCKPGLDRLNPQVPFCVAVTCSQPCNAEEKEQCLKMDNGVMDCVCMPGYQRANGNRKCEECPFGYSGMNCKDQFQLILTIVGTIAGALILILLIAFIVSARSKNKKKDGEEQRLIEDDFHNLRLRQTGFSNLGADNSIFPKVRTGVPSQTPNPYANQRSMPRPDY
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
  • 基因功能参考文献：
    1. these data indicate that combining chemotherapy and MUC13 antagonism could improve the treatment of metastatic cancers PMID: 27399336
    2. Muc13 was upregulated in the fundus of the stomach already 1 day after infection with Helicobacter heilmannii. PMID: 24866791
    3. these studies demonstrate that MUC1 and MUC13 are important components of gastrointestinal homeostasis and that disruption or inappropriate expression of these mucins could predispose to infectious and inflammatory disease and inflammation-induced cancer. PMID: 23149663
    4. protective role in the colonic epithelium by inhibiting toxin-induced apoptosis PMID: 21636645
    5. hypothesize that NJ-1(+)megakaryocytes (MKs) are immature MKs and the NJ-1 molecule is involved in MK adhesion to endothelial cells [NJ-1] PMID: 11922618

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Secreted.
  • 数据库链接：

    KEGG: mmu:17063

    STRING: 10090.ENSMUSP00000023520

    UniGene: Mm.3177