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  4. Recombinant Human Protein BEAN1 (BEAN1)

Recombinant Human Protein BEAN1 (BEAN1)

  • 货号：
    CSB-CF665479HU
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    BEAN1
  • Uniprot No.：
  • 别名：
    BEAN1; Protein BEAN1; Brain-expressed protein associating with Nedd4 homolog; BEAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-259
  • 氨基酸序列
    MSFKRPCPLARYNRTSYFYPTFSESSEHSHLLVSPVLVASAVIGVVIILSCITIIVGSIR RDRQARLQRHRHRHHRHHHHHHHHRRRRHREYEHGYVSDEHTYSRSSRRMRYACSSSEDW PPPLDISSDGDVDATVLRELYPDSPPGYEECVGPGATQLYVPTDAPPPYSLTDSCPTLDG TSDSGSGHSPGRHQQEQRTPAQGGLHTVSMDTLPPYEAVCGAGPPSGLLPLPGPDPGPRG SQGSPTPTRAPASGPERIV
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. this study reveals a regulation mechanism of NEDD4-1 stability by O-GlcNAcylation. PMID: 26876577
    2. SCA31 is associated with "inserted" pentanucleotide repeats containing (TGGAA)n. PMID: 19878914
    3. Our data indicate that SCA31 is absent or rare in the Chinese population on Taiwan. PMID: 21163552
    4. This study describes the structure of SCA31 pentanucleotide repeat sequences in a cohort of Caucasian patients with spinocerebellar ataxia. PMID: 22049201
    5. we conclude that the RNA foci containing BEAN1-direction transcript (UGGAA)n are associated with Purkinje cell degeneration in Spinocerebellar ataxia type 31 PMID: 23607545

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  • 相关疾病：
    Spinocerebellar ataxia 31 (SCA31)
  • 亚细胞定位：
    Membrane; Single-pass membrane protein.
  • 数据库链接：

    HGNC: 24160

    OMIM: 117210

    KEGG: hsa:146227

    STRING: 9606.ENSP00000442793

    UniGene: Hs.740218