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  4. Recombinant Cat Follicle-stimulating hormone receptor (FSHR)

Recombinant Cat Follicle-stimulating hormone receptor (FSHR)

  • 货号：
    CSB-CF702060CA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    FSHR; Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor
  • 种属：
    Felis catus (Cat) (Felis silvestris catus)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    18-695
  • 氨基酸序列
    CHHRICHCWHRVFLCQESKVTEIPSDLPRNAVELRFVLTKLRVIPKGAFSGFGDLEKIEI SQNDVLEVIEANVFFNLSKLHEIRIEKANNLLYIDTDAFQNLPNLRYLLISNTGIKHFPA VHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESMILWLNKNGIQEIHNCAFNGTQLDE LNLSDNINLEELPNDVFQGASGPVILDISRTRIHSLPSYGLENIKKLRAKSTYNLKKLPS LDKFVALMEASLTYPSHCCAFANWRRPISELHPICNKSILRQEVDDMTQARGQRVSLAED EESSYTKGFDMMYSEFDYDLCNEVVDVTCSPKPDAFNPCEDIMGYDILRVLIWFISILAI TGNIIVLMILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIYTKSQYHNYAIDWQ TGAGCDAAGFFTVFASELSVYTLTVITLERWHTITHAMQLECKVQLRHAAIIMLLGWIFA FMVALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICCCYAHIYLTVR NPNIVSSSSDTKIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKSKILLVLFYPI NSCANPFLYAIFTKNFRRDFFILLSKFGCYEVQAQTYRSETSSTAHNFHPRNGHCPPAPR VTNSSNYILIPLRHLAKN
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
  • 基因功能参考文献：
    1. No differences in the ovarian expression of FSHR mRNA, LHR protein or mRNA were found between the pre-pubertal and adult cats, but significantly lower FSHR protein expression was found in pre-pubertal cats compared to adult luteal cats. PMID: 28402061
    2. Results describe the expression of follicle stimulating hormone and luteinizing hormone receptors during follicular growth in the domestic cat ovary. PMID: 17219419
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily
  • 数据库链接：

    KEGG: fca:554348

    STRING: 9685.ENSFCAP00000001126