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  4. Recombinant Xenopus laevis Zinc finger protein ZIC 3 (zic3)

Recombinant Xenopus laevis Zinc finger protein ZIC 3 (zic3)

  • 货号：
    CSB-YP026486XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP026486XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP026486XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP026486XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP026486XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    zic3; zic3-aZinc finger protein ZIC 3; XZic3; XlZic3; Zinc finger protein Zic3-A; Zinc finger protein of the cerebellum 3
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-441
  • 氨基酸序列
    MTMLLDGGPQ FPTLGVGGFG TARHHEMSNR DAGMGLNPFT EPSHAAAFKL SPASHDLSSS QSSAFTPQAS GYASSLGHHA GQVPSYGGAA FNSTRDFLFR NRNSGIADSS SAGSQHGLFA NHGPPGIGEP PGHLIFPGLH EQSSSHTSSN GHVVNGQMHL GLRGDIFGRP DPYRAVPSPR TDHYAAAQFH NYNHMNMSMN VAAHHGQGAF FRYMRQPIKQ ELSCKWLEES TMNHPQKTCD RTFSSMHELV THMTMEHVGG PEQNNHICYW EECPRGGKSF KAKYKLVNHI RVHTGEKPFP CPFPGCGKIF ARSENLKIHK RTHTGEKPFK CEFEGCDRRF ANSSDRKKHM HVHTSDKPYI CKVCDKSYTH PSSLRKHMKV HESQGSDSSP AASSGYESAT PPAMVSANSE EPSKNSSATH QTNNNSHNTG LLPPNFNEWY V
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probably acts as a transcriptional activator. May bind to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. Can determine the ectodermal cell fate and promote the earliest step of neural and neural crest development. Involved in establishing left-right asymmetry in the embryo.
  • 基因功能参考文献：
    1. Zic3 can suppress Wnt/beta-catenin signaling and control development of the notochord and Spemann's organizer. PMID: 22056782
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    GLI C2H2-type zinc-finger protein family
  • 组织特异性：
    First detected at early gastrula (stage 10.25) in the dorsal lip and prospective neural plate. Also expressed in the mesoderm at early gastrulation, with expression strongest on the dorsal side. Mesodermal expression continues at stage 12 but is hardly de
  • 数据库链接：

    KEGG: xla:394375

    UniGene: Xl.7969