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  4. Recombinant Xenopus laevis Eukaryotic translation initiation factor 6 (eif6)

Recombinant Xenopus laevis Eukaryotic translation initiation factor 6 (eif6)

  • 货号：
    CSB-YP007582XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP007582XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP007582XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP007582XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP007582XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    eif6
  • Uniprot No.：
  • 别名：
    eif6Eukaryotic translation initiation factor 6; eIF-6
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-245
  • 氨基酸序列
    MAVRASFENN NEIGCFAKLT NTYCLVAIGG SENFYSVFEG ELSETIPVVH ASIAGCRIIG RMCVGNRHGL MVPNNTTDQE LQHMRNSLPD SVRIQRVEER LSALGNVIAC NDYVALVHPD LDRETEEILA DVLKVEVFRQ TIAEQVLVGS YCAFSNQGGL LHPKTSIEDQ DELSSLLQVP LVTGTVNRGS EVIAAGMVVN DWCAFCGLDT TSTELSVIES VFKLSDAHPS TIATSMRDSL IDSLT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
  • 基因功能参考文献：
    1. aberrant eye phenotype, produced by eif6 overexpression, is not directly linked to the PKC-regulated effects of eif6 on translation and ribosomal subunit interaction PMID: 21601348
    2. The higher presence of p27BBP/eIF6 would appear related to an increased need of apoptosis control in the regions where cell death is essential for normal development. PMID: 20663234
    3. Xp27(BBP)/eIF6 is part of a mechanism acting on the specific translation of messengers regulating cell survival; Xp27(BBP)/eIF6 may regulate the translation of factors upstream of Bcl-2/Bax. PMID: 19779496
    4. The distribution of p27BBP/eIF6 and its association with the cytoskeleton varies according to oogenesis stages. PMID: 15990955
    5. p27BBP/eIF6 expression is modulated during embryogenesis in differentiating anlagens and may suggest a correlation between p27BBP/eIF6 and proliferative activity. PMID: 16425228

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  • 亚细胞定位：
    Cytoplasm. Nucleus, nucleolus.
  • 蛋白家族：
    EIF-6 family
  • 数据库链接：

    KEGG: xla:398731

    UniGene: Xl.5851