Recombinant Staphylococcus aureus Iron-regulated surface determinant protein A (isdA)
In Stock-
货号:CSB-EP763937SKW
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规格:¥2328
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图片:
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP763937SKW could indicate that this peptide derived from E.coli-expressed Staphylococcus aureus (strain MSSA476) isdA.
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Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP763937SKW could indicate that this peptide derived from E.coli-expressed Staphylococcus aureus (strain MSSA476) isdA.
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其他:
产品详情
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纯度:Greater than 85% as determined by SDS-PAGE.
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基因名:isdA
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Uniprot No.:
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别名:isdA; frpA; stbA; SAS1064Iron-regulated surface determinant protein A; Fur-regulated protein A; Staphylococcal transferrin-binding protein A
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种属:Staphylococcus aureus (strain MSSA476)
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蛋白长度:Full Length of Mature Protein
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来源:E.coli
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分子量:35.1 kDa
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表达区域:47-316aa
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氨基酸序列ATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKT
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. -
蛋白标签:N-terminal 10xHis-tagged and C-terminal Myc-tagged
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产品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
缓冲液:Tris-based buffer,50% glycerol
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储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:3-7 business days
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注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet & COA:Please contact us to get it.
引用文献
- Surface plasmon resonance aptasensing and computational analysis of Staphylococcus aureus IsdA surface protein TA Bruce‐Tagoe,Biotechnology progress,/
- Evaluation of three Staphylococcus aureus proteins involved in the adhesion process as antigens for the detection of bovine intramammary infections G Torres,Journal of Medical Microbiology,2023
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靶点详情
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功能:Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source. Receives heme from IsdB and transfers it to IsdC. Plays also a role in the inhibition of host immune response. Protects S.aureus against the bactericidal protease activity of apolactoferrin. Enhances bacterial cellular hydrophobicity, which renders S.aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin. Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization.
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亚细胞定位:Secreted, cell wall; Peptidoglycan-anchor.
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数据库链接:
KEGG: sas:SAS1064
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