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  4. Recombinant Staphylococcus aureus Enterotoxin type E (entE)

Recombinant Staphylococcus aureus Enterotoxin type E (entE)

  • 货号：
    CSB-YP320170FKZ
  • 规格：
    ￥2616
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP320170FKZ could indicate that this peptide derived from Yeast-expressed Staphylococcus aureus entE.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP320170FKZ could indicate that this peptide derived from Yeast-expressed Staphylococcus aureus entE.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 别名：
    entEEnterotoxin type E; SEE
  • 种属：
    Staphylococcus aureus
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    Yeast
  • 分子量：
    28.4kDa
  • 表达区域：
    28-257aa
  • 氨基酸序列
    SEEINEKDLRKKSELQRNALSNLRQIYYYNEKAITENKESDDQFLENTLLFKGFFTGHPWYNDLLVDLGSKDATNKYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWIDGKQTTVPIDKVKTSKKEVTVQELDLQARHYLHGKFGLYNSDSFGGKVQRGLIVFHSSEGSTVSYDLFDAQGQYPDTLLRIYRDNKTINSENLHIDLYLYTT
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：

    A DNA sequence corresponding to 28-257aa of the Staphylococcus aureus Enterotoxin type E (entE) was expressed with an N-terminal 6xHis-tag in the yeast. The resulting protein is a full-length of the mature entE protein. It underwent the validation of LC-MS/MS analysis. Its purity reaches up to 90% determined by SDS-PAGE. It can be used to produce specific antibodies. This recombinant entE protein may also find uses in the studies of entE-associated cell biology.

    As one of the most important microorganisms, Staphylococcus aureus causes various human diseases by secreting virulence factors staphylococcal superantigens (SAgs). EntE, also known as SEE, is one of the toxic SAgs, which can cross-link the T cell receptor (TCR) and major histocompatibility complex class II, triggering a massive T cell activation and hence disease. Depending on the dose and route of exposure, SEE and other SEs can cause food poisoning, acute and fatal respiratory distress, and toxic shock.

  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome.
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Staphylococcal/streptococcal toxin family