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  4. Recombinant Sheep Natriuretic peptides B (NPPB)

Recombinant Sheep Natriuretic peptides B (NPPB)

  • 中文名称：
    绵羊NPPB重组蛋白
  • 货号：
    CSB-YP016021SH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    绵羊NPPB重组蛋白
  • 货号：
    CSB-EP016021SH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    绵羊NPPB重组蛋白
  • 货号：
    CSB-EP016021SH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    绵羊NPPB重组蛋白
  • 货号：
    CSB-BP016021SH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    绵羊NPPB重组蛋白
  • 货号：
    CSB-MP016021SH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    NPPBNatriuretic peptides B; Gamma-brain natriuretic peptide) [Cleaved into: Brain natriuretic peptide 29; BNP-29); Brain natriuretic peptide 26; BNP-26)]
  • 种属：
    Ovis aries (Sheep)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    27-129
  • 氨基酸序列
    HPLG GPGSASELPG LQELLDRLRD RVSELQAEQL RVEPLQQGQG LEETWDSPAA APAGFLGPHH SLLQALRGPK MMRDSGCFGR RLDRIGSLSG LGCNVLRRY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.
  • 基因功能参考文献：
    1. ANP and BNP plasma concentrations are sourced from a single organ (the heart) and are subject to substantial extraction across most tissue beds in experimental heart failure. PMID: 16095755
    2. In a model of congenital cardiac defect with increased pulmonary blood flow, soluble guanylate cyclase alpha (sGCalpha) was greater at 2 & 4 weeks, & sGCbeta & phosphodiesterase 5 (PDE5) were greater at 4 weeks; plasma BNP increased. PMID: 17902145
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Natriuretic peptide family
  • 数据库链接：

    KEGG: oas:100294642

    UniGene: Oar.19888