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  4. Recombinant Sheep Lutropin subunit beta (LHB)

Recombinant Sheep Lutropin subunit beta (LHB)

  • 货号：
    CSB-YP012910SH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP012910SH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP012910SH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP012910SH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP012910SH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    LHB
  • Uniprot No.：
  • 别名：
    LHBLutropin subunit beta; Lutropin beta chain; Interstitial cell-stimulating hormone; Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta) [Cleaved into: LH beta-1; LH beta-2; LH beta-3]
  • 种属：
    Ovis aries (Sheep)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    21-141
  • 氨基酸序列
    SRGPLRPLCQ PINATLAAEK EACPVCITFT TSICAGYCLS MKRVLPVILP PMPQRVCTYH ELRFASVRLP GCPPGVDPMV SFPVALSCHC GPCRLSSTDC GGPRTQPLAC DHPPLPDILF L
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The LH alpha 3/LH beta 3 heterodimer was shown to have potent renotropic and weak gonadotropic activity.
  • 基因功能参考文献：
    1. Data indicate that the neuropeptide RFamide-related peptide 3 (RFRP-3) has no effect onluteinizing hormone secretion. PMID: 26862995
    2. This study indicates that endogenous opiates play a crucial role in the mechanism inhibiting GnRH/LH axis activity in lactating sheep and that the ligands for mu opioid receptor may have the highest inhibitory effect. PMID: 23953813
    3. Data suggest dietary components (phytoestrogens here) down-regulate basal secretion/total production of follicle stimulating hormone (CGA+FSHB) yet up-regulate gonadotropin-releasing hormone agonist-induced LH (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
    4. These results indicate that the reproductive system can respond acutely to infusion of metabolic fuels such as propionate, although a sustained recovery of pulsatile LH secretion requires more than an increase in this single metabolic substrate. PMID: 21668532
    5. In ewes, infusion with genistein decreased the level of LHbeta in the adenohypophysis. PMID: 15531133

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Glycoprotein hormones subunit beta family
  • 数据库链接：

    KEGG: oas:443395

    UniGene: Oar.442