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  4. Recombinant Schizosaccharomyces pombe Kinetochore protein fta2 (fta2)

Recombinant Schizosaccharomyces pombe Kinetochore protein fta2 (fta2)

  • 中文名称：
    庞贝裂殖酵母fta2重组蛋白
  • 货号：
    CSB-YP892186SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    庞贝裂殖酵母fta2重组蛋白
  • 货号：
    CSB-EP892186SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    庞贝裂殖酵母fta2重组蛋白
  • 货号：
    CSB-EP892186SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    庞贝裂殖酵母fta2重组蛋白
  • 货号：
    CSB-BP892186SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    庞贝裂殖酵母fta2重组蛋白
  • 货号：
    CSB-MP892186SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    fta2
  • Uniprot No.：
  • 别名：
    fta2; sma2; SPAC1783.03Inner kinetochore subunit fta2; CENP-P homolog; Constitutive centromere-associated network protein fta2; Sim4 complex subunit fta2; Sim4-mal2-associated protein 2
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-351
  • 氨基酸序列
    MSGRRYSQIS QQEGSSSSDD SDSQQKKTKR TVAHRSPNTT LNGMPRVDSR ARPNENSGQS KSSNGRVDTD RKMDLLRKRS NLVHQTLLLE KEVRVRRNAI NQRDDSFLSG FIKSLLEIDS SVVIYNTENP DNPKTKQVMP SAEPKKHVKL NSSISSIRFT QHEFEAESEK IIHHSLKGDI EYLPSFKFLL EIKVRTIDYA LLFITYKIPH FARKELSSFS DSAIQCLDIV ALLRAFSLFA HHYSYRCNTW FYLSKHMKKV ASANMDAQCF YVQNSFYKIT ILYEIKFDDL GFVQPNYCIS YILKNQNEKI VSITSKLLNQ LDKRFSEFVS LFGFREGSLL LLQALFKPHL G
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore COMA complex, which connects centromere-associated proteins and the outer kinetochore. COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly. Fta2, fta3 and fta4 associate with the central core (cnt) and inner repeat (inr) region of the centromere.
  • 基因功能参考文献：
    1. Kinetochore localization of Mal2 and Fta2 depends on each other, and overexpression of one protein can rescue the phenotype of the mutant version of the other protein. The two proteins appear to have an overlapping function. PMID: 16855021
  • 亚细胞定位：
    Nucleus. Chromosome, centromere, kinetochore.
  • 蛋白家族：
    CENP-P/CTF19 family
  • 数据库链接：

    KEGG: spo:SPAC1783.03

    STRING: 4896.SPAC1783.03.1