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  4. Recombinant Scheffersomyces stipitis Autophagy-related protein 8 (ATG8)

Recombinant Scheffersomyces stipitis Autophagy-related protein 8 (ATG8)

  • 中文名称：
    Recombinant Scheffersomyces stipitis Autophagy-related protein 8(ATG8),Yeast
  • 货号：
    CSB-YP387619SXM
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Scheffersomyces stipitis Autophagy-related protein 8(ATG8),Yeast
  • 货号：
    CSB-EP387619SXM
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Scheffersomyces stipitis Autophagy-related protein 8(ATG8),Yeast
  • 货号：
    CSB-EP387619SXM-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Scheffersomyces stipitis Autophagy-related protein 8(ATG8),Yeast
  • 货号：
    CSB-BP387619SXM
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Scheffersomyces stipitis Autophagy-related protein 8(ATG8),Yeast
  • 货号：
    CSB-MP387619SXM
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ATG8
  • Uniprot No.：
  • 别名：
    ATG8; PICST_34219Autophagy-related protein 8; Autophagy-related ubiquitin-like modifier ATG8
  • 种属：
    Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-116
  • 氨基酸序列
    MRSQFKDEHP FEKRQAEATR IAQRFKDRVP VICEKVENSD IPEIDKRKYL VPVDLSVGQF VYVIRKRIKL PSEKAIFIFV NDILPPTAAL ISTIYEEHKD EDGFLYVLYS GENTFG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
  • 亚细胞定位：
    Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
  • 蛋白家族：
    ATG8 family
  • 数据库链接：

    KEGG: pic:PICST_34219

    STRING: 322104.XP_001387846.1