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  4. Recombinant Saccharomyces cerevisiae Mitochondrial inner membrane protein OXA1 (OXA1), partial

Recombinant Saccharomyces cerevisiae Mitochondrial inner membrane protein OXA1 (OXA1), partial

  • 中文名称：
    酿酒酵母OXA1重组蛋白
  • 货号：
    CSB-YP331102SVG1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母OXA1重组蛋白
  • 货号：
    CSB-EP331102SVG1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母OXA1重组蛋白
  • 货号：
    CSB-EP331102SVG1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母OXA1重组蛋白
  • 货号：
    CSB-BP331102SVG1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母OXA1重组蛋白
  • 货号：
    CSB-MP331102SVG1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    OXA1
  • Uniprot No.：
  • 别名：
    OXA1; PET1402; YER154W; Mitochondrial inner membrane protein OXA1; Cytochrome oxidase biogenesis protein OXA1; Oxidase assembly protein 1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mitochondrial inner membrane insertase that mediates the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the inner membrane. Links mitoribosomes with the inner membrane. Forms pores capable of accommodating translocating protein segments. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the N-terminal part of the COX2 protein into the mitochondrial intermembrane space.
  • 基因功能参考文献：
    1. observations suggest that the function of Oxa1 is relevant not only for the biogenesis of conserved mitochondrial components such as respiratory chain complexes or ABC transporters but also for mitochondria-specific membrane proteins of eukaryotic origin PMID: 22846909
    2. the close proximity of Oxa1 to ribosomes is not only used to improve membrane insertion but is also critical for the productive assembly of the subunits of the cytochrome c oxidase. PMID: 22904327
    3. Oxa1 behaves as a pore-forming translocase that is regulated in a membrane potential and substrate-dependent manner PMID: 22829595
    4. Findings show that the distribution of Oxa1 within the inner membrane is dynamic and adapts to different physiological needs. PMID: 22513091
    5. Deletion of OXA1 impairs the biogenesis of the three respiratory complexes of dual genetic origin. PMID: 15908145
    6. Oxa1 has the ability to accept preproteins within the membrane PMID: 16253275
    7. The phosphatidylethanolamine level of yeast mitochondris is affected by the mitochondrial components OXA1 and YME1. PMID: 17976194
    8. OXA1 complements a lack of yidC2 in S. mutans. PMID: 19366667

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  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    OXA1/ALB3/YidC family
  • 数据库链接：

    KEGG: sce:YER154W

    STRING: 4932.YER154W