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  4. Recombinant Rat Zinc finger protein 667 (Znf667)

Recombinant Rat Zinc finger protein 667 (Znf667)

  • 货号：
    CSB-YP026932RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP026932RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP026932RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP026932RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP026932RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Znf667
  • Uniprot No.：
  • 别名：
    Znf667; Mip1; Mipu1; Zfp667Zinc finger protein 667; Myocardial ischemic preconditioning up-regulated protein 1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-608
  • 氨基酸序列
    MPAARGKSKS KAPVTFGDLA IYFSQEEWEW LSPNQKDLYE DVMLENYHNL VSVGLACRRP NIIALLEKGK APWMVEPSRK RRGPELGSKD ETKKLPPSQC NKSGPSICKK PDSSQQKVPT EKAKHNKNAV PRKNKKGHSG KKSLKCNSCG KTFFRSLSLK LHQGFHTGER SYECSTCGQV FRQILSLILH QRVHTQNKSY ECDKCGDIFN KKLTLMIHRR SHNGKENFHH EKTSDSCPSL SPHHNNHAID SIHQCRKCGK VFSRMSSLLL HKKIHNRKRI QKYSACGRGF KKKPVLVHKR ICIGKKTHEN KALIQSLRQR TYQSENPFTC RKCRKSFSRI SALMLHQRAH TSGNPYKCDK CQKDFGRLST LILHLRIHSG EKQFKCNKCE KVCNRLSSFI QHKKIHKRKK KLIECKECGK MFGGMKNLKV HLNIHSEEKP FKCNKCSKVF GRQSFLSEHQ RIHTGEKPYQ CEECGKAFSH RISLTRHKRI HSEDRPYECD LCGKAFSQSA HLAQHERIHT GEKPYACKIC KKSFTQRISL ILHERSHTGE KPYECNECGK AFSSGSDLIR HQRSHSSEKP YECSKCGKAY SRSSSLIRHQ SIHSEEMS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in transcriptional regulation.
  • 基因功能参考文献：
    1. ZNF667 that confers cytoprotection is a novel regulator of the rat Bax gene. PMID: 25397408
    2. Mipu1 is involved in HIF-1-mediate cytoprotection by inhibiting the expression of Bax and interfering activation of mitochondrial apoptotic pathway. PMID: 24349374
    3. The H(2)O(2)-induced up-regulation of Mipu1 in H9c2 cardiomyocytes was mediated by cAMP/PKA-dependent CREB activation. PMID: 20488243
    4. Results found that Mipu1 was highly expressed in the heart and brain of rats and was localized in the nucleus of H9c2 myogenic cells and lay the foundation for further study of the biological functions of Mipu1. PMID: 19649394
    5. These results suggested that Mipu1 protein might act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions PMID: 19015817
    6. Results indicate that the GC boxes are essential for the activity of the Mipu1 minimal promoter activity PMID: 19352546

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 数据库链接：

    KEGG: rno:308326

    UniGene: Rn.43493