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  4. Recombinant Rat Septin-12 (41529)

Recombinant Rat Septin-12 (41529)

  • 货号：
    CSB-YP703292RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP703292RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP703292RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP703292RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP703292RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Sept12
  • Uniprot No.：
  • 别名：
    Septin12; Sept12; Septin-12
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-356
  • 氨基酸序列
    MDERRTPSPC SSRPSSPRTP PCEMFGPVGI EAVLDQLRIK AMKTGFEFNI MVVGQSGLGK STMVNTLFKS KVWQSPAPNL DVPMPQTLEL HSVTHVIEEK GLKLKLTVTD TPGFGDQINN DKCWDPILSY INQQYEQYLQ EELLITRQRH IPDTRVHCCV YFVPPTGHCL RPLDIEFLRR LCRTVNVVPV IARADSLTIE ERDAFRSRIQ QNLKNHCIDV YPQQCFDEDI NDRLLNSKIR EQIPFAVVGA DREHIVNGRC VLGRKTKWGI IEVENMAHCE FLLLRDLLIR SHLQDLKDIT HNVHYENYRV LRLNESHVLP RGPGWVNLAP ASPGQLMAPG PEKVRKRSKD PRDDEC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins. Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
  • 基因功能参考文献：
    1. Study describes Sept12, a novel septin, identified in a yeast two hybrid screen using Sept5 as the bait; Sept12 protein levels rise upon sexual maturity and the Sept12 protein colocalizes with the annulus in isolated mature spermatozoa. PMID: 17685441
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell projection, cilium, flagellum.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 组织特异性：
    Predominantly expressed in testis and epididymis. Component of the sperm tail annulus (at protein level).
  • 数据库链接：

    KEGG: rno:363542

    STRING: 10116.ENSRNOP00000057921

    UniGene: Rn.123511