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  4. Recombinant Rat Retinoic acid receptor RXR-gamma (Rxrg)

Recombinant Rat Retinoic acid receptor RXR-gamma (Rxrg)

  • 货号：
    CSB-YP685589RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP685589RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP685589RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP685589RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP685589RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Rxrg; Nr2b3; Retinoic acid receptor RXR-gamma; Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-463
  • 氨基酸序列
    MYGNYSHFMK FPTGFGGSPG HTGSTSMSPS VALPTGKPMD SHPSYTDTPV SAPRTLSAVG TPLNALGSPY RVITSAMGPP SGALAAPPGI NLVVPPSSQL NVVNSVSSSE DIKPLPGLPG IGNMNYPSTS PGSLVKHICA ICGDRSSGKH YGVYSCEGCK GFFKRTIRKD LIYTCRDNKD CLIDKRQRNR CQYCRYQKCL VMGMKREAVQ EERQRSRERA ESEAECASTG HEDMPVERIL EAELAVEPKT ESYGDMSVES STNDPVTNIC HAADKQLFTL VEWAKRIPHF SDLTLEDQVI LLRAGWNELL IASFSHRSVS VQDGILLATG LHVHRSSAHS AGVGSIFDRV LTELVSKMKD MRMDKSELGC LRAIVLFNPD AKGLSNPSEV ETLREKVYAT LEAYTKQKYP EQPGRFAKLL LRLPALRSIG LKCLEHLFFF KLIGDTPIDT FLMEMLETPL QIT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
  • 基因功能参考文献：
    1. the results of the present study revealed that miR3305p acts as a critical regulator of RXRgamma, and is able to determinate the fate of MSCs to differentiate into adipocytes. This suggests that miR3305p and RXRgamma may be target molecules for controlling metabolic diseases. PMID: 30015907
    2. RXRgamma was absent in the female rat brain, while it was observed in some regions in the male. PMID: 23017197
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Nuclear hormone receptor family, NR2 subfamily
  • 组织特异性：
    Expressed in the liver, but not detected in the adrenal gland (at protein level). Restricted expression in adrenal gland, kidney, liver, brain and lungs. Strong expression in heart and muscles.
  • 数据库链接：

    KEGG: rno:83574

    STRING: 10116.ENSRNOP00000006117

    UniGene: Rn.40816