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  4. Recombinant Rat Protein Spindly (Ccdc99)

Recombinant Rat Protein Spindly (Ccdc99)

  • 货号：
    CSB-YP663377RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP663377RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP663377RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP663377RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP663377RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Spdl1
  • Uniprot No.：
  • 别名：
    Spdl1; Ccdc99; Protein Spindly; Coiled-coil domain-containing protein 99; Spindle apparatus coiled-coil domain-containing protein 1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-597
  • 氨基酸序列
    MEADITNLRN KLKECEDERL KAAQYGLQLL ERQTELQSQL DKCHEEMMTT AENYNQEKYA LQREVELKSR MLESLSCECE ALRQQQKAQL EQLEMQLHRS HRQEVHGLRN KLENLKVELD EARLSEKQLK QKLDHQGELL SHKSEELRLL SEQRALSSVS SELLSLQTEL TEAEGVKNAL REEVNELQCK QEQLECLNAS LLHQVDRLKE EKEEREKEAV SYYNALEKAR VENQDLQVQL GHALQQAADP NSKGNSLFAE VEDRRVAMER RLNLMKDKYQ SLKKQNAFTR DQMNKMKLQI STLLRMRGSQ TEFEQQERLF AMLEQKNGEI KHLLGEINKL EKFKNLYENM ESKSSTSDSA CALEDSTYYT DLLQLKLDKL NKENESTKGE LSIQRMKALF ESQRTLDIER KLFANERHLQ LSESENLKLR AKLDELKLKY EPEERIEVPV LKRRREVLPL NINTPEETAA ASATGEDVSR LPLERKEESC LDNLKDNTVQ WKQPASLSPH KSLPLDTQPK KEKCVTLVAS PASTEVLHEQ SGNTPSSPRL TEESRLPTKV KERKEATSKL EKGASKKSHT IMYVSSKSTP EMQCPQQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration.
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    Spindly family
  • 数据库链接：

    KEGG: rno:303037

    STRING: 10116.ENSRNOP00000009648

    UniGene: Rn.54949