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  4. Recombinant Rat Plasminogen activator inhibitor 1 RNA-binding protein (Serbp1)

Recombinant Rat Plasminogen activator inhibitor 1 RNA-binding protein (Serbp1)

  • 中文名称：
    大鼠Serbp1重组蛋白
  • 货号：
    CSB-YP738124RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Serbp1重组蛋白
  • 货号：
    CSB-EP738124RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Serbp1重组蛋白
  • 货号：
    CSB-EP738124RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Serbp1重组蛋白
  • 货号：
    CSB-BP738124RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Serbp1重组蛋白
  • 货号：
    CSB-MP738124RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Serbp1
  • Uniprot No.：
  • 别名：
    Serbp1; Pairbp1; Rda288; Plasminogen activator inhibitor 1 RNA-binding protein; PAI1 RNA-binding protein 1; PAI-RBP1; RDA288; SERPINE1 mRNA-binding protein 1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-407
  • 氨基酸序列
    MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG AKSAAQAAAQ TNSNAAGKQL RKESQKDRKN PLPPSVGVAD KKEETQPPVA LKKEGIRRVG RRPDQQLQGD GKIIDRRPER RPPRERRFEK PLEEKGEGGE FSVDRPIIER PIRGRGGLGR GRGGRGRGMG RGDGFDSRGK REFDRHSGSD RSSFSHYSGL KHEDKRGGSG SHNWGTVKDE LTESPKYIQK QISYNCSDLE QSNVTEETPE GEEHPVADTE NKENEVEEVK EEGPKEMTLD EWKAIQNKDR AKVEFNIRKP NEGADGQWKK GFVLHKSKSE EAHAEDSVMD HHFRKPANDI TSQLEINFGD LGRPGRGGRG GRGGRGRGGR PNRGSRTDKS SASAPDVDDP EAFPALA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation.
  • 基因功能参考文献：
    1. These studies support the concept that the interaction between PAIRBP1-PGRMC1 is an essential component of the mechanism through which progesterone inhibits apoptosis. PMID: 23242527
    2. RDA288 in cytoplasm and plasma membrane components of granulosa cells of antral follicles. Present on extracellular surface of plasma membrane. RDA288 plays significant role in mediating progesterone's antiapoptotic action in granulosa cells. PMID: 14988380
    3. PAIRBP1 plays an important role in mediating the antiapoptotic action of progesterone in ovarian granulosa and luteal cells. PMID: 15814896
  • 亚细胞定位：
    Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
  • 数据库链接：

    KEGG: rno:246303

    STRING: 10116.ENSRNOP00000009503

    UniGene: Rn.203108