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  4. Recombinant Rat Paralemmin-1 (Palm)

Recombinant Rat Paralemmin-1 (Palm)

  • 货号：
    CSB-YP838733RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP838733RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP838733RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP838733RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP838733RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Palm
  • Uniprot No.：
  • 别名：
    Palm; Paralemmin-1; Paralemmin
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-380
  • 氨基酸序列
    MEVLATDTVS QQERLQAIAE KRRKQAEIES KRRQLEDDRR QLQYLKSKAL RERWLLEGTP SSASEGDEDM RKQMQEDEQK ARSLEESITR LEKEIDVLEF GESAPAAPKE NSAAPSPIRP HSTSPAKEEQ KSETMVNAQQ TPLGTPKENR KSTPVRSPGG STMMKAAMYS VEITVEKDKV TGETRVLSST TLLPRDPLPQ GVKVYEDETK VVHAVDGLSE NGIQPLSSSE VDELIHKADE VTLSEAGSTT GPAEPRGLAE DVTRTTPSRR EITGVEAQPG EATSGPPGIQ PGQEPPVTMV FMGYQNVEDE AETKKVLGLQ DTIKAELVVI EDSVTPREPA PLNGSAAELP ATKEENQTGP TTTPSDTQDL DMKKPRCRCC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in plasma membrane dynamics and cell process formation. Necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner.
  • 基因功能参考文献：
    1. analysis of the cellular and subcellular localization of paralemmin-1 in the rat tissues is consistent with a role for paralemmin-1 in the formation and stabilization of plasma membrane elaborations, in neurons as well as in other cell types PMID: 16847661
    2. This study identifies a key role for paralemmin-1 in spine maturation through modulation of filopodia induction. PMID: 18287537
  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, filopodium membrane; Lipid-anchor. Cell projection, axon. Cell projection, dendrite. Cell projection, dendritic spine. Basolateral cell membrane; Lipid-anchor. Apicolateral cell membrane; Lipid-anchor.
  • 蛋白家族：
    Paralemmin family
  • 组织特异性：
    Expressed in neurons cells of neuropil-rich areas of the brain, in the Purkinje cells of the cerebellum, in cells of the cerebral cortex, hippocampus, brainstem nuclei and glial processes and sheaths. Expressed in the medulla of the adrenal chromaffin cel
  • 数据库链接：

    KEGG: rno:170673

    STRING: 10116.ENSRNOP00000013762

    UniGene: Rn.198776