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  4. Recombinant Rat Katanin p60 ATPase-containing subunit A1 (Katna1)

Recombinant Rat Katanin p60 ATPase-containing subunit A1 (Katna1)

  • 中文名称：
    大鼠Katna1重组蛋白
  • 货号：
    CSB-YP724969RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Katna1重组蛋白
  • 货号：
    CSB-EP724969RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Katna1重组蛋白
  • 货号：
    CSB-EP724969RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Katna1重组蛋白
  • 货号：
    CSB-BP724969RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Katna1重组蛋白
  • 货号：
    CSB-MP724969RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Katna1
  • Uniprot No.：
  • 别名：
    Katna1; Katanin p60 ATPase-containing subunit A1; Katanin p60 subunit A1; EC 5.6.1.1; p60 katanin
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-491
  • 氨基酸序列
    MSLLMITENV KLAREYALLG NYDSAMVYYQ GVLDQINKYL YSVKDTHLHQ KWQQVWQEIN VEAKHVKEIM KTLESFKLDS TSLKAAQHEL PSSEGEVWSL PVPVERRPLP GPRKRQSTQH SDPKPHSNRP GAVVRAHRPS AQSLHSDRGK AVRSREKKEQ SKGREEKNKL PAAVTEPEAN KFDSTGYDKD LVEALERDII SQNPNVRWYD IADLVEAKKL LQEAVVLPMW MPEFFKGIRR PWKGVLMVGP PGTGKTLLAK AVATECKTTF FNVSSSTLTS KYRGESEKLV RLLFEMARFY SPATIFIDEI DSICSRRGTS EEHEASRRVK AELLVQMDGV GGASENDDPS KMVMVLAATN FPWDIDEALR RRLEKRIYIP LPSAKGREEL LRISLRELEL ADDVNLASIA ENMEGYSGAD ITNVCRDASL MAMRRRIEGL TPEEIRNLSR EEMHMPTTME DFEMALKKVS KSVSAADIER YEKWIVEFGS C
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
  • 基因功能参考文献：
    1. Katanin p60 contributes to microtubule instability around the midbody and facilitates cytokinesis in rat cells. PMID: 24303010
    2. two modes by which microtubule severing occurs during axonal branch formation, based on the concentration of spastin at branch sites and on local detachment from microtubules of molecules such as tau that regulate the severing properties of P60-katanin PMID: 18234839
  • 亚细胞定位：
    Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族：
    AAA ATPase family, Katanin p60 subunit A1 subfamily
  • 数据库链接：

    KEGG: rno:292464

    STRING: 10116.ENSRNOP00000020417

    UniGene: Rn.47464