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  4. Recombinant Rat Inositol-3-phosphate synthase 1 (Isyna1)

Recombinant Rat Inositol-3-phosphate synthase 1 (Isyna1)

  • 货号：
    CSB-YP011856RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP011856RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP011856RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP011856RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP011856RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Isyna1
  • Uniprot No.：
  • 别名：
    Isyna1; Ino1Inositol-3-phosphate synthase 1; IPS 1; EC 5.5.1.4; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthase
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-557
  • 氨基酸序列
    MEPAAEILVD SPDVIFGPEA IEARYEYRTT RVSREGGVLR VRPTATRFTF RTARQVPRLG VMLVGWGGNN GSTLTAAVLA NRLRLTWPTR TGRKEANYYG SLTQAGTVNL GLDGDGREVF VPFSALLPMV APNDLVFDGW DISSLNLAEA MRRAQVLDCG LQEQLWPHME SLRPRPSVYI PEFIAANQTA RADNLIPGTR AQQLEQIRKD IRDFRSSAGL DKVIVLWTAN TERFCEVVPG RNDTAENLLR TIQLGLEVSP STLFAVASIL EGCAFLNGSP QNTLVPGALE LASQRHVFVG GDDFKSGQTK VKSVLVDFLI GSGLKTMSIV SYNHLGNNDG QNLSAPLQFR SKEVTKSSVV DDMVQSNRVL YAPGEEPDHC VVIKYVPYVG DSKRALDEYT SELMLGGTNT LVLHNTCEDS LLAAPIMLDL VLLTELCQRV SFCTDSDPEP QGFHPVLSVL SFLFKAPLVP PGSPVVNALF RQRSCIENIF RACVGLPPQN HMLLEHKMER PFPGIKPEEV KATSPLPCKK ESTPATNGCT GDANGHTQAP TPELSTA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
  • 基因功能参考文献：
    1. Differential phosphorylation of IPS isoforms in brain, intestine and testis suggests novel functions in these tissues. PMID: 23504145
    2. Isyna1 is regulated, in part, by DNA methylation and that significant alterations in methylation patterns during development could have a major impact on inositol phosphate synthase expression in later life. PMID: 21841945
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Myo-inositol 1-phosphate synthase family
  • 数据库链接：

    KEGG: rno:290651

    STRING: 10116.ENSRNOP00000026821

    UniGene: Rn.98850