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  4. Recombinant Rat Ataxin-1 (Atxn1)

Recombinant Rat Ataxin-1 (Atxn1)

  • 货号：
    CSB-YP723589RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP723589RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP723589RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP723589RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP723589RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Atxn1; Sca1Ataxin-1; Spinocerebellar ataxia type 1 protein homolog
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-789
  • 氨基酸序列
    MKSNQERSNE CLPPKKREIP ATSRPSEEKA TALPSDNHCV EGVAWLPSTP GSRGHGGGRH GPAGTSGEHG LQGMGLHKAL SAGLDYSPPS APRSVPTANT LPTVYPPPQS GTPVSPVQYA HLSHTFQFIG SSQYSGPYAG FIPSQLISPP GNPVTSAVAS AAGATTPSQR SQLEAYSTLL ANMGSLSQAP GHKVEPPPQQ HLGRAAGLVN PGSPPPTQQN QYIHISSSPQ SSGRATSPPI PVHLHPHQTM IPHTLTLGPS SQVVVQYSDA GGHFVPREST KKAESSRLQQ AMQAKEVLNG EMEKSRRYGA SSSVELSLGK TSSKSVPHPY ESRHVVVHPS PADYSSRDTS GVRGSVMVLP NSSTPSADLE TQQATHREAS PSTLNDKSGL HLGKPGHRSY ALSPHTVIQT THSASEPLPV GLPATAFYAG AQPPVIGYLS SQQQAITYAG GLPQHLVIPG TQPLLIPVGS PDMDTPGAAS AIVTSSPQFA AVPHTFVTTA LPKSENFNPE ALVTQAAYPA MVQAQIHLPV VQSVASPAAA SPTLPPYFMK GSIIQLANGE LKKVEDLKTE DFIQSAEISN DLKIDSSTVE RIEDSHSPGV AVIQFAVGEH RAQVSVEVLV EYPFFVFGQG WSSCCPERTS QLFDLPCSKL SVGDVCISLT LKNLKNGSVK KGQPVDPASA LLKHAKTDSL AGSRHRYAEQ ENGINQGSAQ VLSENGELKF PEKIGLPAAP FLTKIEPSKP TATRKRRWSA PETRKLEKSE DEPPLTLPKP SLIPQEVKIC IEGRSNVGK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved brain development.
  • 基因功能参考文献：
    1. CD24 and Sca-1 in the mammary glands were expressed at lower level in 6-week-old female rats than in 9-week-old female rats. PMID: 17545040
    2. expression of SCA1 gene is prominent in LH-producing cells and is not under direct control of gonadal factor(s) in both genders PMID: 15514462
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    ATXN1 family
  • 数据库链接：

    KEGG: rno:25049

    STRING: 10116.ENSRNOP00000023140

    UniGene: Rn.88438