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  4. Recombinant Rat Apolipoprotein D (Apod)

Recombinant Rat Apolipoprotein D (Apod)

  • 中文名称：
    Recombinant Rat Apolipoprotein D(Apod),Yeast
  • 货号：
    CSB-YP001935RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Apolipoprotein D(Apod),Yeast
  • 货号：
    CSB-EP001935RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Apolipoprotein D(Apod),Yeast
  • 货号：
    CSB-EP001935RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Apolipoprotein D(Apod),Yeast
  • 货号：
    CSB-BP001935RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Apolipoprotein D(Apod),Yeast
  • 货号：
    CSB-MP001935RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Apod
  • Uniprot No.：
  • 别名：
    ApodApolipoprotein D; Apo-D; ApoD
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    21-189
  • 氨基酸序列
    QSFHLGKCPS PPVQENFDVK KYLGRWYEIE KIPVSFEKGN CIQANYSLME NGNIKVLNKE LRPDGTLNQV EGEAKQSNMS EPAKLEVQFF SLMPPAPYWI LATDYESYAL VYSCTTFFWF FHVDYVWILG RNPYLPPETI TYLKYILTSN DIDIAKITTK DQANCPDFL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    APOD occurs in the macromolecular complex with lecithin-transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
  • 基因功能参考文献：
    1. Collectively, results of this study suggest that Apod is a novel regulatory gene in the male reproductive system, especially in penises of rats fed a high-cholesterol diet, and that expression of Apod is regulated at the posttranscriptional level by target microRNAs. PMID: 27566528
    2. apoD may be part of an intrinsic cardioprotective system, possibly as a consequence of its antioxidation activity. PMID: 24082102
    3. The increased expression of apoD by atypical antipsychotics may reflect a novel molecular mechanism underlying their favorable effects compared with haloperidol on cognition, negative symptoms and extra-pyramidal symptoms in schizophrenia PMID: 12911617
    4. ApoD can be expressed or taken up by SMCs and can regulate their motility in response to growth factors. PMID: 15192024
    5. apoD is involved in regenerative processes and scar formation in the peri-infarct area presumably by enhancing lipid trafficking. PMID: 17851453
    6. Apolipoprotein D exerts neurotrophic and synaptogenic effects in dorsal root ganglion cell cultures. PMID: 19414061
    7. We propose that apoD promotes its neuroprotective effects by binding to arachidonic acid and cholesterol thus preventing their oxidation to neurotoxic products such as 4-hydroxynonenal (4-HNE) and 7-ketocholesterol. PMID: 19429117

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Calycin superfamily, Lipocalin family
  • 组织特异性：
    Expressed in liver, kidney, bladder, adrenal, cerebrum, duodenum, testis, lung, spleen, pancreas, heart and skin.
  • 数据库链接：

    KEGG: rno:25239

    STRING: 10116.ENSRNOP00000064368

    UniGene: Rn.11339