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  4. Recombinant Pig Pulmonary surfactant-associated protein D (SFTPD)

Recombinant Pig Pulmonary surfactant-associated protein D (SFTPD)

  • 中文名称：
    斯克罗法SFTPD重组蛋白
  • 货号：
    CSB-YP865048PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法SFTPD重组蛋白
  • 货号：
    CSB-EP865048PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法SFTPD重组蛋白
  • 货号：
    CSB-EP865048PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法SFTPD重组蛋白
  • 货号：
    CSB-BP865048PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法SFTPD重组蛋白
  • 货号：
    CSB-MP865048PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SFTPD
  • Uniprot No.：
  • 别名：
    SFTPD; Pulmonary surfactant-associated protein D; PSP-D; SP-D; Lung surfactant protein D
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    full length protein
  • 表达区域：
    21-378
  • 氨基酸序列
    AEMKTYSQRA VANACALVMC SPMENGLPGR DGRDGREGPR GEKGDPGLPG AVGRAGMPGL AGPVGPKGDN GSTGEPGAKG DIGPCGPPGP PGIPGPAGKE GPSGQQGNIG PPGTPGPKGE TGPKGEVGAL GMQGSTGARG PAGLKGERGA PGERGAPGSA GAAGPAGATG PQGPSGARGP PGLKGDRGPP GERGAKGESG LPGITALRQQ VETLQGQVQR LQKAFSQYKK VELFPNGRGV GEKIFKTGGF EKTFQDAQQV CTQAGGQMAS PRSETENEAL SQLVTAQNKA AFLSMTDIKT EGNFTYPTGE PLVYANWAPG EPNNNGGSSG AENCVEIFPN GKWNDKACGE LRLVICEF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
  • 基因功能参考文献：
    1. The s demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D. PMID: 22921759
    2. Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety. PMID: 14672916
    3. The presence of SP-D in endothelial cells which is NO-, PI(3)K/Akt- and Erk-dependent is demonstrated. It suggests a protective role of SP-D in these cells. PMID: 19010548
    4. The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen. PMID: 17420052
  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
  • 蛋白家族：
    SFTPD family
  • 数据库链接：

    KEGG: ssc:397198

    STRING: 9823.ENSSSCP00000029281

    UniGene: Ssc.319