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  4. Recombinant Musca domestica Polycomb protein esc (esc)

Recombinant Musca domestica Polycomb protein esc (esc)

  • 货号：
    CSB-YP519413MVC
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP519413MVC
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP519413MVC-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP519413MVC
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP519413MVC
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    esc
  • Uniprot No.：
  • 别名：
    escPolycomb protein esc; Protein extra sex combs
  • 种属：
    Musca domestica (House fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-428
  • 氨基酸序列
    MSKVKADKQS PKENTKAENS DNESIDDTAS VATSTTSRSK SPGSRGRRQS RGHSKSKAKR PAYKYDCHLK EDHGQAIFGV SFNHLLGKDQ SMVFATAGSN RCNIYECPRK GGLKLIMCYA DPDPDEVFYT CSWSYDLKTS APLLATAGYR GVIRVIDIHR NESVGNYVGH GQAINELKFH PRQANLLLSG SKDHAIRLWN IQTHVCIAIF GGVEGHRDEV LSIDFDLRGE RIMSSGMDHS LKLWRIDTPE FKDKIEMSRT FNPNKSQLPF PTIMQHFPEF STRDIHRNYV DCVQWFGDFV LSKSCENSIV CWKPGQLHQT LSQLKPNDPS CTIISEFNYD ECEIWFVRFG FNPWHKIVAL GNQYGKVYVW ELDPSDPRHT HSSTLNNIRC TSIVRQTAFS RDATVLVWVC DDGTVWRWNR RNAEVHTP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Polycomb group (PcG) protein. In contrast to other PcG protein, it is specifically required during the first 6 hours of embryogenesis to establish PcG silencing. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via a methylation of histones, rendering chromatin heritably changed in its expressibility. Component of the Esc/E(z) complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. The Esc/E(z) complex is necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat ESC family