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  4. Recombinant Mpuse Protein delta homolog 2 (Dlk2), partial

Recombinant Mpuse Protein delta homolog 2 (Dlk2), partial

  • 货号：
    CSB-EP812967MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP812967MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP812967MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP812967MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Name:Dlk2 Synonyms:Egfl9
  • Uniprot No.：
  • 别名：
    Dlk2; Egfl9Protein delta homolog 2; DLK-2; Endothelial cell-specific protein S-1; Epidermal growth factor-like protein 9; EGF-like protein 9
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 表达区域：
    27-305
  • 氨基酸序列
    DDCS SHCDLAHGCC APDGSCRCDP GWEGLHCERC VRMPGCQHGT CHQPWQCICH SGWAGKFCDK DEHICTSQSP CQNGGQCVYD GGGEYHCVCL PGFHGRGCER KAGPCEQAGF PCRNGGQCQD NQGFALNFTC RCLAGFMGAH CEVNVDDCLM RPCANGATCI DGINRFSCLC PEGFAGRFCT INLDDCASRP CQRGARCRDR VHDFDCLCPS GYGGKTCELV LPAPEPASVG TPQMPTSAVV VPATGPAPHS AGAGLLRISV KEVVRRQESG LGESS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates adipogenesis.
  • 基因功能参考文献：
    1. Deletion of Dlk2 increased anxiety and depressive-like behaviors and altered the vulnerability to restraint stress. PMID: 28863347
    2. KLF4 mediates the transcriptional regulation of Dlk2 in response to IBMX during the early stages of adipogenesis PMID: 22306741
    3. Our results provide the first characterization of Dlk2 transcripts, map the location of the Dlk2 core promoter, and show the role of Sp1 as a key regulator of Dlk2 transcription PMID: 22185379
    4. Data show that DLK1 and DLK2 act as inhibitory non-canonical protein ligands for the NOTCH1 receptor that modulate NOTCH signaling. PMID: 21419176
    5. Adipogenesis may be modulated by the coordinated expression of Dlk1 and EGFL9/Dlk2. PMID: 17320102

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  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Detected in a number of tissues including lung, brain, adrenal gland, testis, adult liver, placenta, ovary and thymus. Not detected in fetal liver or in adult spleen, muscle and heart.
  • 数据库链接：

    KEGG: mmu:106565

    STRING: 10090.ENSMUSP00000058470

    UniGene: Mm.23633