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  4. Recombinant Mouse Zinc finger X-chromosomal protein (Zfx)

Recombinant Mouse Zinc finger X-chromosomal protein (Zfx)

  • 货号：
    CSB-YP026467MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP026467MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP026467MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP026467MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP026467MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Zfx
  • Uniprot No.：
  • 别名：
    ZfxZinc finger X-chromosomal protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-799
  • 氨基酸序列
    MDEDGLELQQ QAPNSFFDAT GAGATHMDGN QIVVEVQETV YVSDVVDSDI TVHNYVPDDP DSVVIQDVIE DVVIEDVQCT DIMDEADVSE TVIIPEQVLD SDVTEEVSLT HCTVPDDVLA SDITSASISM PEHVLTSESI HVSDVGHVEH VVHDSVVEAE IVTDPLAADV VSEEVLVADC ASEAVIDANG IPVNQQDEEK NNCEDYLMIS LDDAGKIEHD GSSGLTMDNE TEIDPCKVDG TCPEVIKVYI FKADPGEDDL GGTVDIVESE PENEHGVELL DPNNSIRVPR EKMVYMAVND SQQEEEELNV AEIADEVYME VIVGEEDAAA AAAAAVHEQQ VEDNEMKTFM PIAWAAAYGN NSDGIENRNG TASALLHIDE SAGLGRLAKQ KPKKRRRPDS RQYQTAIIIG PDGHPLTVYP CMICGKKFKS RGFLKRHMKN HPEHLAKKKY RCTDCDYTTN KKISLHNHLE SHKLTSKAEK AIECDECGKH FSHAGALFTH KMVHKEKGAN KMHKCKFCEY ETAEQGLLNR HLLAVHSKNF PHICVECGKG FRHPSELKKH MRIHTGEKPY ECQYCEYRSA DSSNLKTHVK TKHSKEMPFK CDICLLTFSD TKEVQQHALV HQESKTHQCL HCDHKSSNSS DLKRHIISVH TKDYPHKCDM CDKGFHRPSE LKKHVAAHKG KKMHQCRHCD FKIADPFVLS RHILSVHTKD LPFRCKRCRK GFRQQSELKK HMKTHSGRKV YQCEYCEYST TDASGFKRHV ISIHTKDYPH RCEYCKKGFR RPSEKNQHIM RHHKEVGLP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable transcriptional activator.
  • 基因功能参考文献：
    1. our findings show that RNAi-mediated disruption of Zfx/Zfy in mouse testis affected X/Y spermatogenesis. Additionally, results suggest that the paralogous genes Zfx/Zfy play an important role in the process of X and Y sperm development. The individual interference of Zfx/Zfy may predict the outcome of X and Y haploid sperms. Presented herein is an advanced method developed to control mouse X/Y spermatogenesis and sex rati PMID: 28251288
    2. Zfx is a common cell-intrinsic regulator of diverse Hedgehog-induced tumors. PMID: 25164012
    3. Zfx, a transcription factor that controls hematopoietic stem cell self-renewal, controls the initiation and maintenance of acute myeloid leukemia. PMID: 24485662
    4. These studies identify Zfx as a shared transcriptional regulator of embryonic stem cells and hematopoietic stem cells, suggesting a common genetic basis of self-renewal in embryonic and adult SC. PMID: 17448993
    5. Zfx restrains the stress response and couples antigen receptor signaling to cell expansion and maintenance during B-cell development and peripheral homeostasis PMID: 19329779

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family, ZFX/ZFY subfamily
  • 数据库链接：

    KEGG: mmu:22764

    STRING: 10090.ENSMUSP00000085423

    UniGene: Mm.919